ω-3 Arachidonic Acid - ≥98%, 10mg/ml in ethanol , CAS No.24880-40-8

CAS: 24880-40-8 Cat. No.: A339719 Summenformel: C₂₀H₃₂O₁ Molekulargewicht: 304.5

GRADE & PURITY ≥98%, 10mg/ml in ethanol

Synonyms

2-Amino-4-nitro-N-phenylaniline | 8Z,11Z,14Z,17Z-EICOSA-8,11,14,17-TETRAENOIC ACID (ETA) | omega'-3 Arachidonic Acid | (Z,Z,Z,Z)-eicosa-8,11,14,17-tetraenoic acid | SB67081 | all-cis-8,11,14,17-eicosatetraenoic acid | Bishomostearidonic acid | NCGC0018456

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Übersicht

ω-3 Arachidonic acid is a rare PUFA found in trace amounts in dietary sources. ω-3 fatty acids are known to be essential for infant development and protect against heart disease, hypertension, thrombosis, and autoimmune and inflammatory disorders. In human cell cultures, ω-3 arachidonic acid has been shown to inhibit arachidonoyl-CoA synthetase (K|i|= 14 μM). Additionally, it has been shown to inhibit arachidonoyl-CoA synthetase in calf brain extracts (IC|50|value of about 5μM).

Specifications

Synonyme

2-Amino-4-nitro-N-phenylaniline | 8Z,11Z,14Z,17Z-EICOSA-8,11,14,17-TETRAENOIC ACID (ETA) | omega'-3 Arachidonic Acid | (Z,Z,Z,Z)-eicosa-8,11,14,17-tetraenoic acid | SB67081 | all-cis-8,11,14,17-eicosatetraenoic acid | Bishomostearidonic acid | NCGC0018456

Spezifikationen & Reinheit

≥98%, 10mg/ml in ethanol

Storage

Protected from light,Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Reinheit

≥98%

Produkteigenschaften

Ki-Daten

Arachidonoyl-CoA synthetase: Ki= 14 μM (human platelet membranes)

Namen und Kennungen

Pubchem Sid

528768909

Kanonisches Lächeln

CCC=CCC=CCC=CCC=CCCCCCCC(=O)O

IUPAC Name

(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoic acid

InChIKey

HQPCSDADVLFHHO-LTKCOYKYSA-N

INCHI

1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10,12-13H,2,5,8,11,14-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-,13-12-

Isomere SMILES

CC/C=C\C/C=C\C/C=C\C/C=C\CCCCCCC(=O)O

UN-Nummer

1170

Verpackungsgruppe

II

Molekulargewicht

304.5

Reaxy-Rn

14937615

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=14937615&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Klasse Fatty Acyls
      • Subclass Fatty acids and conjugates

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Klasse: Fatty Acyls
• Subclass: Fatty acids and conjugates
• Intermediate Tree Nodes: Not available
• Direct Parent: Long-chain fatty acids
• Alternative Parents: Unsaturated fatty acids Straight chain fatty acids Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Long-chain fatty acid - Unsaturated fatty acid - Straight chain fatty acid - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic acyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as long-chain fatty acids. These are fatty acids with an aliphatic tail that contains between 13 and 21 carbon atoms.
• External Descriptors: Unsaturated fatty acids

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemische und physikalische Eigenschaften

• Löslichkeit: Soluble in water (1.7 mg/ml at 25° C), 0.1 M Na2CO3, ethanol, DMSO (~100 mg/ml), and DMF (~100 mg/ml).
• Empfindlichkeit: Moisture sensitive；light sensitive
• Brechungsindex: n20D1.50 (Predicted)
• Siedepunkt (°C): 78-80° C
• Schmelzpunkt (°C): -144.0° C
• Molekulargewicht: 304.500 g/mol
• XLogP3: 6.300
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 14
• Exact Mass: 304.24 Da
• Monoisotopic Mass: 304.24 Da
• Topological Polar Surface Area: 37.300 Ų
• Heavy Atom Count: 22
• Formal Charge: 0
• Complexity: 362.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 4
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 4
• Covalently-Bonded Unit Count: 1