≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
4-Hydroxy Propofol is a metabolite of Propofol , a phenol derivative that is suggested to modulate the sensitivity of capsaicin to the transient receptor potential vanilloid subtype-1 (TRPV1) receptor. TRPV1 is a Capsaicin receptor that behaves as a non-selective cation channel that is mainly found in the sensory neurons, and specifically detects painful stimuli, low pH and heat. Studies show that Propofol modifies the kinetics of calcium channels without disturbing the conductance of the channels. In the presence of Propofol, calcium channels have been found to remain closed more time than open. Reports suggest that Propofol acts at GABA|A|receptors in spinal cord studies, intensifies the ATP-activated currents of P2X4 receptor channels present in HEK 293 cells, and activate PKCε.
| Pubchem Sid | 528760980 |
|---|---|
| Kanonisches Lächeln | CC(C)C1=CC(=CC(=C1O)C(C)C)O |
| IUPAC Name | 2,6-di(propan-2-yl)benzene-1,4-diol |
| InChIKey | UFWIJKBKROBWTG-UHFFFAOYSA-N |
| INCHI | 1S/C12H18O2/c1-7(2)10-5-9(13)6-11(8(3)4)12(10)14/h5-8,13-14H,1-4H3 |
| Isomere SMILES | CC(C)C1=CC(=CC(=C1O)C(C)C)O |
| Molekulargewicht | 194.27 |
| Reaxy-Rn | 1950488 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1950488&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Klasse | Benzene and substituted derivatives |
| Subclass | Cumenes |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Cumenes |
| Alternative Parents | Phenylpropanes Hydroquinones 1-hydroxy-2-unsubstituted benzenoids Organooxygen compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Phenylpropane - Cumene - Hydroquinone - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aromatic homomonocyclic compound |
| Beschreibung | This compound belongs to the class of organic compounds known as cumenes. These are aromatic compounds containing a prop-2-ylbenzene moiety. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Datum | Artikel |
|---|---|---|---|
 J2425579 | Certificate of Analysis | Oct 16, 2024 | H332707 |
| J2425580 | Certificate of Analysis | Oct 16, 2024 | H332707 |
| J2425581 | Certificate of Analysis | Oct 16, 2024 | H332707 |
| J2425582 | Certificate of Analysis | Oct 16, 2024 | H332707 |
| Löslichkeit | Soluble in Chloroform |
|---|---|
| Empfindlichkeit | Air sensitive |
| Schmelzpunkt (°C) | 103-105° C |
| Molekulargewicht | 194.270 g/mol |
| XLogP3 | 3.500 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 2 |
| Exact Mass | 194.131 Da |
| Monoisotopic Mass | 194.131 Da |
| Topological Polar Surface Area | 40.500 Ų |
| Heavy Atom Count | 14 |
| Formal Charge | 0 |
| Complexity | 159.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
