4-Hydroxy-TEMPO - ≥98% , CAS No.2226-96-2
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SKU
H104510
Membrane permeable superoxide scavenger. SOD mimetic.
TEMPOL is a superoxide dismutase mimetic that belongs to a class of non-thiol-containing radiation protectors, and has the ability to permeate the membrane. In the presence of TEMPOL, cerebral vessel remodeling is blocked and collagen IV mRNA expression levels are elevated in normotensive and hypertensive rat studies. TEMPOL has been shown to restore the oxidative stress and cardiac dysfunction induced by TNF-α and in PC-12 cells has revealed neuroprotective effects. Additionally, it has shown to decrease blood pressure and sympathetic nerve activity in DOCA-salt rat studies.
product description：
4-Hydroxy-TEMPO is a 4-substituted 2,2,6,6-tetramethylpiperidyl-1-oxy (TEMPO) derivative. It is a low-molecular weight compound and has been proposed as superoxide dismutase mimic.
Weitere Informationen
| CAS | 2226-96-2 |
|---|---|
| Synonyme | 4-Hydroxy-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical | 4-Hydroxy-TEMPO Free Radical | TEMPOL Free Radical |
| Spezifikationen & Reinheit | ≥98% |
| Storage | Store at 2-8°C,Argon charged |
| Verschickt in | Wet ice |
| Product Description | TEMPOL is a superoxide dismutase mimetic that belongs to a class of non-thiol-containing radiation protectors, and has the ability to permeate the membrane. In the presence of TEMPOL, cerebral vessel remodeling is blocked and collagen IV mRNA expression levels are elevated in normotensive and hypertensive rat studies. TEMPOL has been shown to restore the oxidative stress and cardiac dysfunction induced by TNF-α and in PC-12 cells has revealed neuroprotective effects. Additionally, it has shown to decrease blood pressure and sympathetic nerve activity in DOCA-salt rat studies. product description： 4-Hydroxy-TEMPO is a 4-substituted 2,2,6,6-tetramethylpiperidyl-1-oxy (TEMPO) derivative. It is a low-molecular weight compound and has been proposed as superoxide dismutase mimic. |
| Pubchem Sid | 508814175 |
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/508814175 |
| Löslichkeit | Easily soluble in organic solvents such as ethanol and benzene, and easily soluble in water. |
| Empfindlichkeit | light sensitive & Moisture sensitive |
| Mdl-Nummer | MFCD00006478 |
| EG-Nummer | 218-760-9 |
| PubChem CID | 137994 |
| Molekulare Formel | C9H18NO2 |
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