5-Methoxyquinolin-8-amine - ≥97% , CAS No.30465-68-0

CAS: 30465-68-0 Cat. No.: M192632 Summenformel: C₁₀H₁₀N₂O Molekulargewicht: 174.2 EG-Nummer: 842-342-0

GRADE & PURITY ≥97%

Synonyms

A820582 | Oprea1_798026 | 8-Amino-5-methoxyquinoline, 95% | F19180 | Z364003430 | 5-methoxyquinolin-8-amine | 5-methoxy-8-quinolinamine | 5-Methoxy-quinolin-8-ylamine | STK309777 | A820385 | LCZC1977 | 5-methoxy-8-aminoquinoline | AKOS000129566 | EN300-14

Storage

Argon charged,Room temperature

Shipped In

Normal

Übersicht

8-Amino-5-methoxychinolin ist ein substituiertes Chinolinderivat, das mit 5-Chlor-2-nitroanilin als Ausgangsstoff hergestellt werden kann. Es kann als leicht entfernbare Leitgruppe fungieren und auch eine C-H-Aktivierung vermitteln. Diese Eigenschaften haben sich bei der Synthese isomerer Dibenzoxazepinone und komplexer Pyrrolidinone aus Verbindungen mit 8-Amino-5-methoxychinolin-Anteil als nützlich erwiesen.

Anwendung：

Das Chen-Hilfsmittel hat sich als wirksame Leitgruppe bei der Synthese von Pyrrolidonen erwiesen, da es die Aktivierung von C(sp3)-H-Bindungen unterstützt. Es lässt sich leicht durch die Bildung von Amidbindungen installieren und unter milden Bedingungen mit CAN bei Raumtemperatur entfernen.

Specifications

Synonyme

A820582 | Oprea1_798026 | 8-Amino-5-methoxyquinoline, 95% | F19180 | Z364003430 | 5-methoxyquinolin-8-amine | 5-methoxy-8-quinolinamine | 5-Methoxy-quinolin-8-ylamine | STK309777 | A820385 | LCZC1977 | 5-methoxy-8-aminoquinoline | AKOS000129566 | EN300-14

Spezifikationen & Reinheit

≥97%

Storage

Argon charged,Room temperature

Verschickt in

Normal

Reinheit

≥97%

Namen und Kennungen

Pubchem Sid

488191466

Kanonisches Lächeln

COC1=C2C=CC=NC2=C(C=C1)N

IUPAC Name

5-methoxyquinolin-8-amine

InChIKey

MFLLTRMMFHENCM-UHFFFAOYSA-N

INCHI

1S/C10H10N2O/c1-13-9-5-4-8(11)10-7(9)3-2-6-12-10/h2-6H,11H2,1H3

Isomere SMILES

COC1=C2C=CC=NC2=C(C=C1)N

Molekulargewicht

174.2

Reaxy-Rn

143401

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=143401&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Klasse Quinolines and derivatives
      • Subclass Aminoquinolines and derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Klasse: Quinolines and derivatives
• Subclass: Aminoquinolines and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Aminoquinolines and derivatives
• Alternative Parents: Methoxyanilines Anisoles Alkyl aryl ethers Pyridines and derivatives Heteroaromatic compounds Azacyclic compounds Primary amines Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Aminoquinoline - Methoxyaniline - Anisole - Alkyl aryl ether - Pyridine - Benzenoid - Heteroaromatic compound - Ether - Azacycle - Organic nitrogen compound - Hydrocarbon derivative - Primary amine - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Organic oxygen compound - Amine - Aromatic heteropolycyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as aminoquinolines and derivatives. These are organic compounds containing an amino group attached to a quinoline ring system.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemische und physikalische Eigenschaften

• Empfindlichkeit: Air sensitive
• Molekulargewicht: 174.200 g/mol
• XLogP3: 1.700
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 174.079 Da
• Monoisotopic Mass: 174.079 Da
• Topological Polar Surface Area: 48.100 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 174.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Häufig gestellte Fragen

What is the purity of this product?

This product is supplied at ≥97% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at room temperature under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships under standard ambient conditions. No temperature-controlled packaging is required.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 30465-68-0, the molecular formula is C10H10N2O, and the molecular weight is 174.2 g/mol. InChIKey MFLLTRMMFHENCM-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.