A-485 - Moligand™, 10 mM in DMSO , CAS No.1889279-16-6

CAS: 1889279-16-6 Cat. No.: A1493948 Summenformel: C25H24F4N4O5 Molekulargewicht: 536.48
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Deutschland (EU)
USA*
Price
Qty
1ml
A1493948-1ml
Auf Bestellung · 8–12 Wochen
180,40€
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Übersicht

A-485 is a potent and selective catalytic inhibitor of p300/CBP with IC 50 s of 9.8?nM and 2.6?nM for p300 and CBP histone acetyltransferase (HAT), respectively.

Specifications

Spezifikationen & Reinheit
Moligand™, 10 mM in DMSO
Storage
Store at -80°C
Verschickt in
Dry ice packs + Cold packs
Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.
Note
Moligand™
Aktionsart
INHIBITOR
Namen und Kennungen
Isomere SMILES C[C@@H](C(F)(F)F)N(CC1=CC=C(C=C1)F)C(=O)CN2C(=O)[C@]3(CCC4=C3C=CC(=C4)NC(=O)NC)OC2=O
Molekulargewicht 536.48

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
FAQs und Artikel
Citations of This Product
Referenzen
1. Junhui Lv, Zhinang Yin, Conghui Li, Honglin Wen, Jian Ni, Peiyuan Yang, Zemin Song, Ying Xiang, Honghong Wang, Rui Lu, Li Huang, Ying Zhou, Hai-Bing Zhou, Ruijing Xiao, Pingping Fang, Kaiwei Liang.  (2025)  KAT6A chimeras form a self-reinforcing epigenetic module with NURF and MLL/COMPASS to sustain AML.  GENOME BIOLOGY,      [PMID:40830799] [10.1186/s13059-025-03743-y]
2. Zongxin Zhu, Ximiao Chen, Hanwen Zhang, Ronghui Miao, Huiling Yu, Shiying Zhao, Youli Zhang, Tanxin Yu, Di Zhang, Yifei Zhou, Xiaolei Zhang, Wei Zhang.  (2026)  Lactate-driven H3K27 lactylation promotes Olig2-dependent remyelination and motor recovery after spinal cord injury.  NEUROPHARMACOLOGY,      [PMID:41525841] [10.1016/j.neuropharm.2026.110832]
Lösungsrechner
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Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

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