α-Thrombin , CAS No.9002-04-4

CAS: 9002-04-4 Cat. No.: np330890 Summenformel: C₁₂H₁₀ClN₃S Molekulargewicht: 263.75 EG-Nummer: 232-648-7 PubChem CID: 65045

GRADE & PURITY Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, from Human plasma; ≥2700 NIH U/mg protein; Pre-lyophilization Protein Concentration: See COA

Accession #

P00734

Bioactivity

≥2700 NIH U/mg protein

Übersicht

The Human Thrombin was activated from homogeneous human prothrombin by activation with Factor Xa, Factor Va, and phospholipid. These activating enzymes were removed after activation. Complete activation was observed on SDS-PAGE. This activated enzyme has a minimum activity of 2,700 NIH units/mg when compared to NIH standard thrombin.

Extinction Coefficient (1%) = 18.3 

The above protein was purified from Human plasma units that test negative for antibodies to HBc, HCV, HIV 1/2, HTLV-I/II, and non reactive for HBsAg, HIV-1 RNA, HCV RNA, HBV DNA and Syphilis by FDA approved tests. Donors are screened for CJD.

Protein is for research use only; not for human use.

Specifications

Product Name

α-Thrombin , CAS No.9002-04-4

Synonyme

Human Alpha Thrombin | Human α-Thrombin | Human alpha-Thrombin Native Protein | Factor IIa, Human Plasma | Coagulation factor IIa | F2 | PT | THPH1 | RPRGL2

Note

ActiBioPure™, Bioactive, High Performance, Native, EnzymoPure™

Spezifikationen & Reinheit

Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, from Human plasma; ≥2700 NIH U/mg protein; Pre-lyophilization Protein Concentration: See COA

Biochemische und physiologische Mechanismen

Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. Activates coagulation

Bioaktivität

≥2700 NIH U/mg protein

Beitritt #

P00734

Voraussichtliches Molekulargewicht

37 kDa

CAS

9002-04-4

Enzym Kommissionsnummer

EC 3.4.21.5

Molekültyp

Enzyme

Product Line

biological_products

Produkteigenschaften

Perlmutt

NA.54

Lagerung und Versand

Konzentration

from Human plasma; ≥2700 NIH U/mg protein; Pre-lyophilization Protein Concentration: See COA

Rekonstitution

We suggest hydrating the protein with a good quality water to the original volume (See COA). After hydration aliquot into a useful (one time use) size and freeze at -80℃.

Storage

Store at 2-8°C

Verschickt in

Wet ice

Stabilität und Lagerung

Store at 2-8℃ long term. Upon reconstitution, it is recommended to aliquot and freeze at -80℃.