Abemaciclib-d8 - ≥99% , CAS No.2088650-53-5

CAS: 2088650-53-5 Cat. No.: A649748 Summenformel: C₂₇H₂₄D₈F₂N₈ Molekulargewicht: 514.64

GRADE & PURITY ≥99%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Übersicht

Abemaciclib-d 8 is the deuterium labeled Abemaciclib. Abemaciclib (LY2835219) is a selective CDK4/6 inhibitor with IC50 values of 2 nM and 10 nM for CDK4 and CDK6 , respectively.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Specifications

Spezifikationen & Reinheit

≥99%

Biochemische und physiologische Mechanismen

Abemaciclib-d 8 is the deuterium labeled Abemaciclib. Abemaciclib (LY2835219) is a selective CDK4/6 inhibitor with IC50 values of 2 nM and 10 nM for CDK4 and CDK6 , respectively.

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

INHIBITOR

Reinheit

≥99%

Namen und Kennungen

• Molekulargewicht: 514.64

Chemische und physikalische Eigenschaften

• Löslichkeit: DMSO : 5 mg/mL (9.72 mM; ultrasonic and warming and heat to 60°C)