ADDA 5 hydrochloride - 10mM in DMSO , CAS No.473268-46-1

CAS: 473268-46-1 Cat. No.: A655201 Summenformel: C₂₄H₃₆ClNO₂ Molekulargewicht: 406 PubChem CID: 2882960

GRADE & PURITY 10mM in DMSO

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

ADDA 5 hydrochloride is a partial non-competitive inhibitor of cytochrome c oxidase (CcO) , with IC 50 s of 18.93 μM and 31.82 μM for purified CcO from human glioma and bovine heart, respectively.

In Vitro

ADDA 5 hydrochloride is a partial non-competitive inhibitor of CcO, with IC 50 s of 18.93 μM and 31.82 μM for purified CcO from human glioma and bovine heart, respectively. ADDA 5 inhibits CcO activity in UTMZ and Jx22-derived GSCs, with IC 50 s of 21.4 ± 3.9 μM and 15.5 ± 2.8 μM. ADDA 5 (25 μM) shows a growth inhibitory effect on UTMZ cells, with an EC 50 of 8.17 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

ADDA 5 (8 mg/kg, i.p.) significantly suppresses the growth of tumor in mice. ADDA 5 does not causes detectable toxicity at up to 80 mg/kg in mice . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:IC50: 18.93 μM (CcO, human glioma), 31.82 μM (CcO, bovine heart)

Specifications

Spezifikationen & Reinheit

10mM in DMSO

Biochemische und physiologische Mechanismen

ADDA 5 hydrochloride is a partial non-competitive inhibitor of cytochrome c oxidase (CcO) , with IC 50 s of 18.93 μM and 31.82 μM for purified CcO from human glioma and bovine heart, respectively.

Storage

Desiccated,Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

INHIBITOR

Namen und Kennungen

• Isomere SMILES: C1CN(CC2=CC=CC=C21)CC(COCCC34CC5CC(C3)CC(C5)C4)O.Cl
• PubChem CID: 2882960
• Molekulargewicht: 406

Häufig gestellte Fragen

How should this product be stored?

Store at ?80 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 473268-46-1, the molecular formula is C24H36ClNO2, and the molecular weight is 406 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.