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· · COA & SDS für jedes Produkt verfügbar · Versand am selben Tag auf Lager AG14361 - Moligand™, ≥98% , Inhibitor of poly(ADP-ribose) polymerase 1, CAS No.328543-09-5, Inhibitor of poly(ADP-ribose) polymerase 1
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% Synonyms
SCHEMBL476278 | DTXSID80186513 | AB03409 | HMS2210M16 | AKOS016347360 | J-507662 | 1-(4-((dimethylamino)methyl)phenyl)-8,9-dihydro-2,7,9a-triazabenzo[cd]azulen-6(7H)-one | 1-(4-((dimethylamino)methyl)phenyl)-8,9-dihydro-2,7,9a-triazabenzo[cd]azulen-6(7H)-
Storage
Lagerung bei -20°C
Shipped In
Eistruhe + Eispads
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Why this grade Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Lagerung bei -20°C Ships Eistruhe + Eispads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Übersicht AG14361 ist ein potenter Inhibitor von PARP1 mit einem Ki von <5 nM. Er ist mindestens 1000-mal stärker als die Benzamide.
Specifications Synonyme
SCHEMBL476278 | DTXSID80186513 | AB03409 | HMS2210M16 | AKOS016347360 | J-507662 | 1-(4-((dimethylamino)methyl)phenyl)-8,9-dihydro-2,7,9a-triazabenzo[cd]azulen-6(7H)-one | 1-(4-((dimethylamino)methyl)phenyl)-8,9-dihydro-2,7,9a-triazabenzo[cd]azulen-6(7H)-
Spezifikationen & Reinheit
Moligand™, ≥98%
Biochemische und physiologische Mechanismen
Die Behandlung mit AG14361 vor der Bestrahlung erhöht statistisch signifikant die Empfindlichkeit von Mäusen mit LoVo-Xenotransplantaten gegenüber der Strahlentherapie. AG14361 erhöht statistisch signifikant die bl
Storage
Lagerung bei -20°C
Verschickt in
Eistruhe + Eispads
Mechanismus der Wirkung
Inhibitor of poly(ADP-ribose) polymerase 1
Namen und Kennungen Pubchem Sid 528763054 Kanonisches Lächeln CN(C)CC1=CC=C(C=C1)C2=NC3=CC=CC4=C3N2CCNC4=O IUPAC Name 2-[4-[(dimethylamino)methyl]phenyl]-1,3,10-triazatricyclo[6.4.1.04,13]trideca-2,4,6,8(13)-tetraen-9-one InChIKey SEKJSSBJKFLZIT-UHFFFAOYSA-N INCHI 1S/C19H20N4O/c1-22(2)12-13-6-8-14(9-7-13)18-21-16-5-3-4-15-17(16)23(18)11-10-20-19(15)24/h3-9H,10-12H2,1-2H3,(H,20,24) Isomere SMILES CN(C)CC1=CC=C(C=C1)C2=NC3=CC=CC4=C3N2CCNC4=O Molekulargewicht 320.4 Reaxy-Rn 9283091 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9283091&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Klasse Benzimidazoles Subclass Phenylbenzimidazoles Intermediate Tree Nodes Not available Direct Parent Phenylbenzimidazoles Alternative Parents 1,4-benzodiazepines Phenylimidazoles Phenylmethylamines Benzylamines 1,4-diazepines Aralkylamines N-substituted imidazoles Vinylogous amides Heteroaromatic compounds Lactams Secondary carboxylic acid amides Amino acids and derivatives Trialkylamines Azacyclic compounds Organic oxides Hydrocarbon derivatives Organopnictogen compounds Organooxygen compounds Molecular Framework Aromatic heteropolycyclic compounds Substituents Phenylbenzimidazole - Benzodiazepine - 2-phenylimidazole - 1,4-benzodiazepine - Benzylamine - Phenylmethylamine - Para-diazepine - Aralkylamine - Monocyclic benzene moiety - N-substituted imidazole - Benzenoid - Vinylogous amide - Azole - Heteroaromatic compound - Imidazole - Tertiary aliphatic amine - Tertiary amine - Secondary carboxylic acid amide - Amino acid or derivatives - Carboxamide group - Lactam - Azacycle - Carboxylic acid derivative - Amine - Organopnictogen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxygen compound - Organooxygen compound - Organic oxide - Organic nitrogen compound - Aromatic heteropolycyclic compound Beschreibung This compound belongs to the class of organic compounds known as phenylbenzimidazoles. These are compounds containing a phenylbenzimidazole skeleton, which consists of a benzimidazole moiety where its imidazole ring is attached to a phenyl group. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D-Struktur Zugehörige Ziele (menschlich) Zugehörige Ziele (nicht menschlich) Wirkungsmechanismen Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm) Chemische und physikalische Eigenschaften Löslichkeit DMSO ≥20mg/mL Water <1.2mg/mL Ethanol ≥11mg/mL Molekulargewicht 320.400 g/mol XLogP3 1.900 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 3 Rotatable Bond Count 3 Exact Mass 320.164 Da Monoisotopic Mass 320.164 Da Topological Polar Surface Area 50.200 Ų Heavy Atom Count 24 Formal Charge 0 Complexity 460.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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View Moligand™ grade guide →
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