Alicapistat - Moligand™, 10 mM in DMSO , CAS No.1254698-46-8

CAS: 1254698-46-8 Cat. No.: A1494217 Summenformel: C₂₅H₂₇N₃O₄ Molekulargewicht: 433.50 PubChem CID: 67095330

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

Alicapistat (ABT-957) is an orally active selective inhibitor of human calpains 1 and 2 for the potential application of Alzheimer's disease (AD). Alicapistat mitigates the metabolic liability of carbonyl reduction and inhibits calpain 1 with an IC 50 value of 395 nM.

Specifications

Spezifikationen & Reinheit

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Aktionsart

INHIBITOR

Namen und Kennungen

Isomere SMILES

C1CC(=O)N([C@H]1C(=O)NC(CC2=CC=CC=C2)C(=O)C(=O)NC3CC3)CC4=CC=CC=C4

Alternative CAS-Nummer

1254698-46-8

PubChem CID

67095330

MeSH-Eintrag

1-benzyl-N-(4-(cyclopropylamino)-3,4-dioxo-1-phenyl-2-butanyl)-5-oxo-D-prolinamide;2-pyrrolidinecarboxamide, N-(3-(cyclopropylamino)-2,3-dioxo-1-(phenylmethyl)propyl)-5-oxo-1-(phenylmethyl)-, (2R)-;ABT-957;alicapistat

Molekulargewicht

433.50