Allylthiourea - 10mM in DMSO , CAS No.109-57-9

CAS: 109-57-9 Cat. No.: A408879 Molecular Weight: 116.18 Beilstein Registry Number: 1071470 EC Number: 203-683-5
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GRADE & PURITY 10mM in DMSO
Synonyms
Thiourea, N-2-propen-1-yl-
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Status
Price
Qty
1ml
A408879-1ml
2
$19.90
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 12 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Information

Allylthiourea Allylthiourea is a metabolic inhibitor that selective inhibits ammonia oxidation .
In vitro

Allylthiourea selectively inhibits ammonia oxidation at concentrations 8-80 μM. Allylthiourea (1 μM)inhibits ammonia oxidation by 80%. Complete inhibition is observed at an Allylthiourea concentration of 86 μM. The inhibition of Allylthiourea on ammonia oxidation probably acts through chelating the copper of the ammonia monooxygenase active site. Allylthiourea is able to produce soluble methane monooxygenase (sMMO) in the presence of copper. Addition of 25 μM Allylthiourea decreases intracellular copper by 48% in Methylosinus trichosporium OB3b, allowing sMMO production at Cu/biomass ratios normally not permitting sMMO synthesis, which achieves a plateau of 320 μmol naphthol formed per gram dry biomass per hour.

In vivo


Cell Data

cell lines:HeLa, HCT-116, A375, SK-OV-3, MDA-MB-231, and PC-3 cells

Concentrations:

Incubation Time:

Powder Purity:≥99%

Specifications

Synonyms
Thiourea, N-2-propen-1-yl-
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
Allylthiourea is a metabolic inhibitor that selective inhibits ammonia oxidation.
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers
Isomeric SMILES C=CCNC(=S)N
WGK Germany 3
RTECS YR8050000
UN Number 2811
Packing Group I
Molecular Weight 116.18
Beilstein 1071470
Reaxy-Rn 1071470
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1071470&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Melt Point(°C)70-72°C
Citations of This Product
References
1. Weiping Chen, Bingzheng Wang, Yaqing Wang, Ji Li.  (2023)  Understanding the cometabolic degradation of sulfadiazine by an enriched ammonia oxidizing bacteria culture from both extracellular and intracellular perspectives.  CHEMOSPHERE,      [PMID:37330061] [10.1016/j.chemosphere.2023.139244]
2. Jian Zhao, Shangbiao Fang, Weixiao Qi, Huijuan Liu, Jiuhui Qu.  (2022)  Do NH4+-N and AOB affect atenolol removal during simulated riverbank filtration?.  CHEMOSPHERE,      [PMID:35447203] [10.1016/j.chemosphere.2022.134653]
3. Shiyun Tang, Yuanxing Duan, Feng Chang, Wei Jiang, Fengmei Zhang, Zhihua Liu, Yuting Yang, Chunbo Liu, Yingzhuang Chen.  (2020)  The fabrication of carboxylic acid-functionalized porous layer open tube column and its application in hydrophilic interaction chromatography for small polar molecules.  JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES,      [PMID:] [10.1080/10826076.2020.1848864]
4. Donghui Kou, Wei Ma, Shufen Zhang.  (2020)  Functionalized Mesoporous Photonic Crystal Film for Ultrasensitive Visual Detection and Effective Removal of Mercury (II) Ions in Water.  ADVANCED FUNCTIONAL MATERIALS,  31  (9): (2007032).  [PMID:] [10.1002/adfm.202007032]
5. Qiugen Zhang, Jingyi Wu, Xubiao Luo.  (2016)  Facile preparation of a novel Hg(II)-ion-imprinted polymer based on magnetic hybrids for rapid and highly selective removal of Hg(II) from aqueous solutions.  RSC Advances,  (18): (14916-14926).  [PMID:] [10.1039/C5RA22008D]
6. Meng-yu Li, Bo-xuan Zhang, Lu-lu Chen, Jun-jun Kong, Yu-feng Wang, Miao Ba.  (2023)  Spontaneous directed leaching of slippery lubricant in self-stratified marine antifouling coatings for nonporous surfaces.  PROGRESS IN ORGANIC COATINGS,      [PMID:] [10.1016/j.porgcoat.2023.107858]
7. Mengyu Li, Liyang Nan, Boxuan Zhang, Junjun Kong, Yufeng Wang, Miao Ba.  (2023)  Polyether-Thiourea-Siloxane Copolymer Based on H-Bonding Interaction for Marine Antifouling.  MOLECULES,  28  (8): (3574).  [PMID:37110807] [10.3390/molecules28083574]
8. Chuning Zhang, Huaqiang Chu, Qian Ma, Yanyan Chen, Jianwei Fan.  (2023)  Enhanced Heterogeneous Activation of Peroxymonosulfate by Nitrogen–Sulfur Co-Doped Mofs-Derived Carbon.  Applied Sciences-Basel,  13  (5): (3182).  [PMID:] [10.3390/app13053182]
9. Wenjie Wei, Fenghong Lu, Lixiu Cui, Yu Zhang, Yanze Wei, Lingbo Zong.  (2022)  S heteroatom doping in highly porous carbonaceous spheres for boosted oxygen reduction reaction of atomically dispersed Fe–N4 active sites.  CARBON,      [PMID:] [10.1016/j.carbon.2022.06.015]
10. Yu Xiaoqi, Ma Xiaojun, Pan Ziming, Ma Xiaoyun, Ji Xinglong, Lv Yin, Wei Zhong.  (2024)  Preparation of 3D Cellulose-Carbon Quantum Dots Hydrogels for Adsorption of Mercury from Aqueous Solution.  JOURNAL OF POLYMERS AND THE ENVIRONMENT,      [PMID:] [10.1007/s10924-023-03172-7]
11. Xiujuan Zhong, Wang Zhan, Li Ma, Guolu Yin, Guolu Yin.  (2024)  Trace detection of cadmium (II) ions based on an excessively tilted fiber grating.  OPTICS EXPRESS,  32  (9): (15851-15861).  [PMID:38859225] [10.1364/OE.521146]
12. Xiaohui Sun, Linglong Wang, Yongxiao Tuo, Bangyan Zhang, Tao Gan, Jiansong Miao, Chunming Xu.  (2025)  Syngas evolution through CO2 electroreduction over sulfur-bridged electron deficient cobalt and nickel dual atom catalysts.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.165199]
Solution Calculators
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