Amifostine - Moligand™, 10 mM in Water , CAS No.20537-88-6

CAS: 20537-88-6 Cat. No.: A1499392 Summenformel: C5H15N2O3PS Molekulargewicht: 214.22 EG-Nummer: 633-786-4
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in Water
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Deutschland (EU)
USA*
Price
Qty
1ml
A1499392-1ml
Auf Bestellung · 8–12 Wochen
66,73€
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, 10 mM in Water Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 5 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Übersicht

Amifostine (WR2721) is a broad-spectrum cytoprotective agent and a radioprotector. Amifostine selectively protects normal tissues from damage caused by radiation and chemotherapy. Amifostine is potent hypoxia-inducible factor-α1 (HIF-α1) and p53 inducer. Amifostine protects cells from damage by scavenging oxygen-derived free radicals. Amifostine reduces renal toxicity and has antiangiogenic action .

Specifications

Spezifikationen & Reinheit
Moligand™, 10 mM in Water
Storage
Store at -80°C
Verschickt in
Dry ice packs + Cold packs
Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.
Note
Moligand™
Produkteigenschaften
ALogP-4.5
Namen und Kennungen
Isomere SMILES C(CN)CNCCSP(=O)(O)O
Molekulargewicht 214.22
Reaxy-Rn 2088122
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2088122&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Citations of This Product
Referenzen
1. Haijie Wu, Xiaohu Shi, Yingda Zang, Xiaodi Zhao, Xikun Liu, Weida Wang, Wenying Shi, Clarence T.T. Wong, Li Sheng, Xiaoguang Chen, Sen Zhang.  (2023)  7-hydroxycoumarin-β-D-glucuronide protects against cisplatin-induced acute kidney injury via inhibiting p38 MAPK-mediated apoptosis in mice.  LIFE SCIENCES,      [PMID:37336359] [10.1016/j.lfs.2023.121864]
2. Huan Liu, Longsheng Wang, Xiaokai Shi, Lei Yin, Wei Zhai, Shenglin Gao, Yonghui Chen, Tao Zhang.  (2024)  Calcium saccharate/DUSP6 suppresses renal cell carcinoma glycolytic metabolism and boosts sunitinib efficacy via the ERK-AKT pathway.  BIOCHEMICAL PHARMACOLOGY,      [PMID:38697311] [10.1016/j.bcp.2024.116247]
3. Ying-Da Zang, Hai-Jie Wu, Xin-Yi Chen, Zhi-Ling Ma, Chuang-Jun Li, Jie Ma, Xiao-Guang Chen, Li Sheng, Sen Zhang, Dong-Ming Zhang.  (2024)  Synthesis and Biological Evaluation of Novel Psidium Meroterpenoid Derivatives against Cisplatin-Induced Acute Kidney Injury.  JOURNAL OF MEDICINAL CHEMISTRY,      [PMID:39137258] [10.1021/acs.jmedchem.4c01099]
4. Yuwei Yang, Peng Ni, Lixue Ma, Haikang Tang, Jiaming Yang, Xiaoliang Zhou, Yikun Sun, Wenqing Xu.  (2025)  Therapeutic effects of G90′-ES2 protein complex from regenerated Eisenia fetida on radiation-induced skin injury.  JOURNAL OF ETHNOPHARMACOLOGY,      [PMID:40953774] [10.1016/j.jep.2025.120583]
5. Kai Deng, Gaoyuan Zhang, Qiang Yan, Shuwen Han, Yunyao Wei, Ying Mei.  (2026)  Integrating multi-omics reveals the protective effects of Lycium ruthenicum anthocyanins against radiation pneumonitis through gut-lung axis modulation.  TISSUE & CELL,      [PMID:42456388] [10.1016/j.tice.2026.103756]
Lösungsrechner
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