Amino-PEG4-CH2COOH - ≥95% , CAS No.195071-49-9

CAS: 195071-49-9 Cat. No.: A412460 Summenformel: C₁₀H₂₁NO₆ Molekulargewicht: 251.28

GRADE & PURITY ≥95%

Synonyms

3,6,9,12-Tetraoxatetradecanoic acid, 14-amino- | 14-amino-3,6,9,12-tetraoxatetradecanoic acid | H2N-PEG4-CH2COOH | NH2-PEG4-CH2COOH | SCHEMBL1170690 | Amine-PEG4-CH2COOH | AKOS028109928 | Amino-PEG4-CH2COOH | BS-25456 | s10597 | 14-Amino-3,6,9,12-tetraoxa

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Application

227,228,229

Übersicht

Information

Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. Amino-PEG4-CH2COOH is also a non-cleavable 4-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

Specifications

Synonyme

3,6,9,12-Tetraoxatetradecanoic acid, 14-amino- | 14-amino-3,6,9,12-tetraoxatetradecanoic acid | H2N-PEG4-CH2COOH | NH2-PEG4-CH2COOH | SCHEMBL1170690 | Amine-PEG4-CH2COOH | AKOS028109928 | Amino-PEG4-CH2COOH | BS-25456 | s10597 | 14-Amino-3,6,9,12-tetraoxa

Spezifikationen & Reinheit

≥95%

Biochemische und physiologische Mechanismen

Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be applied into the synthesis of PROTACs. Amino-PEG4-CH2COOH is also a non-cleavable 4-unit PEG ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

Storage

Protected from light,Store at -20°C,Argon charged

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Reinheit

≥95%

Namen und Kennungen

Pubchem Sid

528763298

Kanonisches Lächeln

C(COCCOCCOCCOCC(=O)O)N

IUPAC Name

2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetic acid

InChIKey

NPRAKTLKDKKZAV-UHFFFAOYSA-N

INCHI

1S/C10H21NO6/c11-1-2-14-3-4-15-5-6-16-7-8-17-9-10(12)13/h1-9,11H2,(H,12,13)

Isomere SMILES

C(COCCOCCOCCOCC(=O)O)N

Molekulargewicht

251.28

Reaxy-Rn

20360792

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=20360792&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Klasse Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Ebene5 Amino acids and derivatives
          • Ebene6 Amino acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Klasse: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives
• Direct Parent: Amino acids
• Alternative Parents: Monocarboxylic acids and derivatives Dialkyl ethers Carboxylic acids Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Amino acid - Carboxylic acid - Dialkyl ether - Ether - Monocarboxylic acid or derivatives - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Carbonyl group - Amine - Hydrocarbon derivative - Organic nitrogen compound - Organic oxide - Organic oxygen compound - Aliphatic acyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as amino acids. These are organic compounds that contain at least one carboxyl group and one amino group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemische und physikalische Eigenschaften

• Löslichkeit: Solubility (25°C) In vitro
• Empfindlichkeit: 对光敏感
• Molekulargewicht: 251.280 g/mol
• XLogP3: -4.000
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 13
• Exact Mass: 251.137 Da
• Monoisotopic Mass: 251.137 Da
• Topological Polar Surface Area: 100.000 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 178.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1