Amitriptyline-d6 Hydrochloride - ≥99 atom% D,≥98% , CAS No.203645-63-0

CAS: 203645-63-0 Cat. No.: A357463 Summenformel: C₂₀H₁₈D₆ClN Molekulargewicht: 319.90 EG-Nummer: 846-446-7

GRADE & PURITY ≥99 atom% D,≥98%

Synonyms

3-(5,6-dihydrodibenzo[1,2-a:2',1'-d][7]annulen-11-ylidene)-N,N-bis(trideuteriomethyl)propan-1-amine;hydrochloride | 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine-d6 Hydrochloride

Storage

Store at 2-8°C,Protected from light

Shipped In

Wet ice

Übersicht

Amitriptyline-d6 (hydrochloride) is the deuterium labeled Amitriptyline hydrochloride. Amitriptyline hydrochloride is an inhibitor of serotonin reuptake transporter (SERT) and noradrenaline reuptake transporter (NET), with Kis of 3.45 nM and 13.3 nM for human SERT and NET, respectively. Amitriptyline hydrochloride also weakly binds to dopamine reuptake transporter (DAT) with a Ki of 2.58 μM. Amitriptyline hydrochloride also inhibits adrenergic, muscarinic, histamine and 5-HT receptors. Amitriptyline hydrochloride is a TrkA and TrkB receptors agonist with potent neurotrophic activity. Amitriptyline hydrochloride has antidepressant activity

Specifications

Synonyme

3-(5,6-dihydrodibenzo[1,2-a:2',1'-d][7]annulen-11-ylidene)-N,N-bis(trideuteriomethyl)propan-1-amine;hydrochloride | 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine-d6 Hydrochloride

Spezifikationen & Reinheit

≥99 atom% D,≥98%

Storage

Store at 2-8°C,Protected from light

Verschickt in

Wet ice

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Reinheit

≥99 atom% D,≥98%

Namen und Kennungen

• Pubchem Sid: 528773940
• Kanonisches Lächeln: CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl
• IUPAC Name: 3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)-N,N-bis(trideuteriomethyl)propan-1-amine;hydrochloride
• InChIKey: KFYRPLNVJVHZGT-TXHXQZCNSA-N
• INCHI: 1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H/i1D3,2D3
• Isomere SMILES: [2H]C([2H])([2H])N(CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31)C([2H])([2H])[2H].Cl
• Alternative CAS-Nummer: 549-18-8（Unlabelled ）
• UN-Nummer: 2811
• Verpackungsgruppe: III
• Molekulargewicht: 319.90
• Reaxy-Rn: 4164595
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4164595&ln=

Chemische und physikalische Eigenschaften

• Empfindlichkeit: Light sensitive；Moisture sensitive
• Schmelzpunkt (°C): 192-195° C