Anamorelin hydrochloride - ≥99% , Ghrelin receptor agonist, CAS No.861998-00-7, Ghrelin receptor agonist

CAS: 861998-00-7 Cat. No.: A650216 Summenformel: C₃₁H₄₃ClN₆O₃ Molekulargewicht: 583.16 PubChem CID: 16072155

GRADE & PURITY ≥99%

Synonyms

Anamorelin hydrochloride | AC-29222 | SCHEMBL4535148 | ONO-7643 hydrochloride | MFCD23098788 | Anamorelin hydrochloride [USAN] | Q27261306 | Anamorelin hydrochloride (JAN/USAN) | RC-1291 hydrochloride;ONO-7643 hydrochloride

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

Übersicht

AnaMorelin hydrochloride (RC-1291 hydrochloride) is a novel ghrelin receptor agonist(EC50 : 0.74 nM, in the FLIPR assay).

Specifications

Synonyme

Anamorelin hydrochloride | AC-29222 | SCHEMBL4535148 | ONO-7643 hydrochloride | MFCD23098788 | Anamorelin hydrochloride [USAN] | Q27261306 | Anamorelin hydrochloride (JAN/USAN) | RC-1291 hydrochloride;ONO-7643 hydrochloride

Spezifikationen & Reinheit

≥99%

Biochemische und physiologische Mechanismen

Anamorelin (RC-1291) hydrochloride is a potent ghrelin receptor agonist with EC 50 value of 0.74 nM in the FLIPR assay.

Storage

Store at 2-8°C,Desiccated

Verschickt in

Wet ice

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

AGONIST

Mechanismus der Wirkung

Ghrelin receptor agonist

Reinheit

≥99%

Namen und Kennungen

Pubchem Sid

528776304

Kanonisches Lächeln

CC(C)(C(=O)N[C@H](CC1=CNC2=CC=CC=C21)C(=O)N3CCC[C@](C3)(CC4=CC=CC=C4)C(=O)N(C)N(C)C)N.Cl

IUPAC Name

2-amino-N-[(2R)-1-[(3R)-3-benzyl-3-[dimethylamino(methyl)carbamoyl]piperidin-1-yl]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-methylpropanamide;hydrochloride

InChIKey

VFYAEUWJFGTGGO-GHTUPXNNSA-N

INCHI

1S/C31H42N6O3.ClH/c1-30(2,32)28(39)34-26(18-23-20-33-25-15-10-9-14-24(23)25)27(38)37-17-11-16-31(21-37,29(40)36(5)35(3)4)19-22-12-7-6-8-13-22;/h6-10,12-15,20,26,33H,11,16-19,21,32H2,1-5H3,(H,34,39);1H/t26-,31-;/m1./s1

Isomere SMILES

CC(C)(C(=O)N[C@H](CC1=CNC2=CC=CC=C21)C(=O)N3CCC[C@](C3)(CC4=CC=CC=C4)C(=O)N(C)N(C)C)N.Cl

Alternative CAS-Nummer

249921-19-5

PubChem CID

16072155

Molekulargewicht

583.16

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Klasse Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Ebene5 Peptides
          • Ebene6 Dipeptides

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Klasse: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Peptides
• Direct Parent: Dipeptides
• Alternative Parents: N-acyl-alpha amino acids and derivatives 3-benzylpiperidines Tryptamines and derivatives Alpha amino acid amides 3-alkylindoles Piperidinecarboxamides N-acylpiperidines Substituted pyrroles Benzene and substituted derivatives Tertiary carboxylic acid amides Heteroaromatic compounds Secondary carboxylic acid amides Carboxylic acid hydrazides Azacyclic compounds Carbonyl compounds Hydrocarbon derivatives Hydrochlorides Monoalkylamines Organic oxides
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Alpha-dipeptide - N-acyl-alpha amino acid or derivatives - Benzylpiperidine - 3-benzylpiperidine - Alpha-amino acid amide - Triptan - Alpha-amino acid or derivatives - 3-alkylindole - Indole - Indole or derivatives - N-acyl-piperidine - 3-piperidinecarboxamide - Piperidinecarboxamide - Monocyclic benzene moiety - Piperidine - Substituted pyrrole - Benzenoid - Pyrrole - Tertiary carboxylic acid amide - Heteroaromatic compound - Amino acid or derivatives - Secondary carboxylic acid amide - Carboxamide group - Carboxylic acid hydrazide - Organoheterocyclic compound - Azacycle - Primary amine - Primary aliphatic amine - Hydrocarbon derivative - Organic oxide - Organonitrogen compound - Organooxygen compound - Carbonyl group - Organic nitrogen compound - Hydrochloride - Amine - Organic oxygen compound - Aromatic heteropolycyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemische und physikalische Eigenschaften

• Löslichkeit: DMSO : 170 mg/mL (291.52 mM; Need ultrasonic) H2O : 50 mg/mL (85.74 mM; ultrasonic and warming and heat to 60°C)
• Empfindlichkeit: Moisture sensitive
• Molekulargewicht: 583.200 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 9
• Exact Mass: 582.309 Da
• Monoisotopic Mass: 582.309 Da
• Topological Polar Surface Area: 115.000 Ų
• Heavy Atom Count: 41
• Formal Charge: 0
• Complexity: 904.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3