Apolipoprotein E from Human Plasma

Cat. No.: np001130

GRADE & PURITY Bioactive, Native, ≥95%(SDS-PAGE), See COA

Accession #

P02649

Übersicht

Apolipoprotein E serves as a ligand for low density receptors and participates in the transport and redistribution of cholesterol and other lipids. Other functions include immunoregulation and cell growth modulation and differentiation. Apo E is thought to be involved in tissue repair as increased amounts of the protein are found at sites of peripheral nerve injury and regeneration. A mutant form is associated with familial type III hyperlipoproteinemia. The concentration of Apo E in normal plasma is 5 mg per 100 ml.

Researchers' source for Alzheimer's Disease Research.

Extinction Coefficient: 1.31  

Prepared from fresh, non-frozen plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

Aladdin products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research use only.

Specifications

Product Name

Apolipoprotein E from Human Plasma

Synonyme

Apolipoprotein E, Human Plasma | APOE | AD2 | LPG | APO-E | ApoE4 | LDLCQ5

Note

Bioactive, Native

Spezifikationen & Reinheit

Bioactive, Native, ≥95%(SDS-PAGE), See COA

Biochemische und physiologische Mechanismen

Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues. Post-translational: Synthesized with the

Beitritt #

P02649

Voraussichtliches Molekulargewicht

34 kDa

Molekültyp

Protein

Lagerung und Versand

Form

Frozen in 50 mM NH4HCO3, pH 8.0

Konzentration

See COA

Storage

Store at -80°C,Avoid repeated freezing and thawing

Verschickt in

Dry ice packs + Cold packs

Stabilität und Lagerung

Store at -80℃ long term (>1 year). Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle.