APS-2-79 - 10mM in DMSO , CAS No.2002381-31-7

CAS: 2002381-31-7 Cat. No.: A422437 Summenformel: C23H22ClN3O3 Molekulargewicht: 423.89 EG-Nummer: 110-852-6
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GRADE & PURITY 10mM in DMSO
Synonyms
6,7-dimethoxy-N-(2-methyl-4-phenoxyphenyl)quinazolin-4-amine hydrochloride;6,7-dimethoxy-N-(2-methyl-4-phenoxyphenyl)quinazolin-4-aminehydrochloride
Storage
Protected from light,Store at -80°C
Shipped In
Dry ice packs + Cold packs
Size
Deutschland (EU)
USA*
Price
Qty
1ml
A422437-1ml
2 Auf Lager

99,70€

117,06€
Speichern 17,35 € (14.83%)
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Protected from light,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Übersicht

Shipped at 4°C. Store at -20°C. Store In the Dark. Store under desiccating conditions.

Specifications

Synonyme
6,7-dimethoxy-N-(2-methyl-4-phenoxyphenyl)quinazolin-4-amine hydrochloride;6,7-dimethoxy-N-(2-methyl-4-phenoxyphenyl)quinazolin-4-aminehydrochloride
Spezifikationen & Reinheit
10mM in DMSO
Biochemische und physiologische Mechanismen
APS-2-79 is a stabilizer of the Kinase suppressor of Ras (KSR) inactive state, resulting in inhibition of oncogenic Ras signaling, antagonizing the Ras–MAPK pathway. KSR is a MAPK scaffold that is regulated allosterically by dimerization with RAF. APS-2-7
Storage
Protected from light,Store at -80°C
Verschickt in
Dry ice packs + Cold packs
Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.
Aktionsart
ANTAGONIST
Namen und Kennungen
Pubchem Sid528762095
Kanonisches LächelnCC1=C(C=CC(=C1)OC2=CC=CC=C2)NC3=NC=NC4=CC(=C(C=C43)OC)OC.Cl
IUPAC Name6,7-dimethoxy-N-(2-methyl-4-phenoxyphenyl)quinazolin-4-amine;hydrochloride
InChIKeyLIXKSHWZJNNZHG-UHFFFAOYSA-N
INCHI1S/C23H21N3O3.ClH/c1-15-11-17(29-16-7-5-4-6-8-16)9-10-19(15)26-23-18-12-21(27-2)22(28-3)13-20(18)24-14-25-23;/h4-14H,1-3H3,(H,24,25,26);1H
Molekulargewicht 423.89
Reaxy-Rn 33754141
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=33754141&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D-Struktur
Interaktives chemisches Strukturmodell





Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot NumberCertificate TypeDatumArtikel
H2421339Certificate of AnalysisJul 02, 2026 A422437
Chemische und physikalische Eigenschaften
Molekulargewicht423.900 g/mol
XLogP3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass423.135 Da
Monoisotopic Mass423.135 Da
Topological Polar Surface Area65.500 Ų
Heavy Atom Count30
Formal Charge0
Complexity502.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count2
Lösungsrechner
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