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· · COA & SDS für jedes Produkt verfügbar · Versand am selben Tag auf Lager ARN-509 - Moligand™, ≥98% , Androgen Receptor antagonist, CAS No.956104-40-8, Androgen Receptor antagonist
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% Synonyms
Uremide | Erleada (TN) | Z2037280438 | Erleada | HY-16060 | 4-{7-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl}-2-fluoro-N-methylbenzamide | APALUTAMIDE [MI] | SCHEMBL909297 | CCG-264760 | MFCD22380626 | NCG
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Übersicht ARN-509 is a selective and competitive androgen receptor inhibitor with IC50 of 16 nM in a cell-free assay, useful for prostate cancer treatment.
Specifications Synonyme
Uremide | Erleada (TN) | Z2037280438 | Erleada | HY-16060 | 4-{7-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl}-2-fluoro-N-methylbenzamide | APALUTAMIDE [MI] | SCHEMBL909297 | CCG-264760 | MFCD22380626 | NCG
Spezifikationen & Reinheit
Moligand™, ≥98%
Biochemische und physiologische Mechanismen
ARN-509 is an androgen receptor antagonist with potential antineoplastic activity. ARN-509 binds to AR in target tissues thereby preventing androgen-induced receptor activation and facilitating the formation of inactive complexes that can
Verschickt in
Ice chest + Ice pads
Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.
Mechanismus der Wirkung
Androgen Receptor antagonist
Produkteigenschaften Namen und Kennungen Pubchem Sid 528763123 Kanonisches Lächeln CNC(=O)C1=C(C=C(C=C1)N2C(=S)N(C(=O)C23CCC3)C4=CC(=C(N=C4)C#N)C(F)(F)F)F IUPAC Name 4-[7-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamide InChIKey HJBWBFZLDZWPHF-UHFFFAOYSA-N INCHI 1S/C21H15F4N5O2S/c1-27-17(31)13-4-3-11(8-15(13)22)30-19(33)29(18(32)20(30)5-2-6-20)12-7-14(21(23,24)25)16(9-26)28-10-12/h3-4,7-8,10H,2,5-6H2,1H3,(H,27,31) Isomere SMILES CNC(=O)C1=C(C=C(C=C1)N2C(=S)N(C(=O)C23CCC3)C4=CC(=C(N=C4)C#N)C(F)(F)F)F Molekulargewicht 477.43 Reaxy-Rn 18291651 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=18291651&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Klasse Azolidines Subclass Imidazolidines Intermediate Tree Nodes Not available Direct Parent Phenylimidazolidines Alternative Parents 2-halobenzoic acids and derivatives Alpha amino acids and derivatives N-phenylthioureas Benzamides Benzoyl derivatives Fluorobenzenes Pyridines and derivatives Imidazolidinones Aryl fluorides Vinylogous halides Heteroaromatic compounds Thioureas Secondary carboxylic acid amides Nitriles Azacyclic compounds Carbonyl compounds Hydrocarbon derivatives Organic oxides Alkyl fluorides Organofluorides Molecular Framework Aromatic heteropolycyclic compounds Substituents Phenylimidazolidine - Alpha-amino acid or derivatives - N-phenylthiourea - 2-halobenzoic acid or derivatives - Halobenzoic acid or derivatives - Benzamide - Benzoic acid or derivatives - Benzoyl - Fluorobenzene - Halobenzene - Aryl fluoride - Aryl halide - Monocyclic benzene moiety - Benzenoid - Imidazolidinone - Pyridine - Heteroaromatic compound - Vinylogous halide - Thiourea - Secondary carboxylic acid amide - Carboxamide group - Nitrile - Carbonitrile - Carboxylic acid derivative - Azacycle - Organooxygen compound - Organic oxide - Organohalogen compound - Carbonyl group - Alkyl fluoride - Cyanide - Organic nitrogen compound - Organic oxygen compound - Organosulfur compound - Hydrocarbon derivative - Alkyl halide - Organofluoride - Organonitrogen compound - Aromatic heteropolycyclic compound Beschreibung This compound belongs to the class of organic compounds known as phenylimidazolidines. These are polycyclic compounds containing an imidazoline substituted by a phenyl group. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D-Struktur Zugehörige Ziele (menschlich) Zugehörige Ziele (nicht menschlich) Wirkungsmechanismen Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm) Chemische und physikalische Eigenschaften Löslichkeit DMSO 15 mg/mL Ethanol 5 mg/mL Molekulargewicht 477.400 g/mol XLogP3 3.000 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 9 Rotatable Bond Count 3 Exact Mass 477.088 Da Monoisotopic Mass 477.088 Da Topological Polar Surface Area 121.000 Ų Heavy Atom Count 33 Formal Charge 0 Complexity 886.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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