Artemisone - 10mM in DMSO , CAS No.255730-18-8

CAS: 255730-18-8 Cat. No.: A656464 Summenformel: C₁₉H₃₁NO₆S Molekulargewicht: 401.52 PubChem CID: 11531457

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

Artemisone (Artemifone) is a potent and semi-synthetic antimalarial , inhibits P. falciparum strains, with a mean IC 50 of 0.83 nM Artemisone is also a potent inhibitor of human CMV .

In Vitro

Artemisone inhibits 3D7 and K1 P. falciparum , with IC 50 s of 0.88±0.59 and 1.23±0.64 nM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Artemisone is effectve at inhibiting the parasitaemia in the P. berghei NY susceptible strain, with an ED 50 of 9.62 mg/kg via subcutaneous route and 11.67 mg/kg via oral administration . Artemisone (3, 1, 0.3 and 0.1 mg/kg, s.c.) in combination with ohter antimalarials has enhanced effect against the chloroquine-resistant line P. yoelii NS MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:Plasmodium

Specifications

Spezifikationen & Reinheit

10mM in DMSO

Biochemische und physiologische Mechanismen

Artemisone (Artemifone) is a potent and semi-synthetic antimalarial , inhibits P. falciparum strains, with a mean IC 50 of 0.83 nM. Artemisone is also a potent inhibitor of human CMV.

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

INHIBITOR

Namen und Kennungen

• Isomere SMILES: C[C@@H]1CC[C@H]2[C@H]([C@@H](O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)N5CCS(=O)(=O)CC5)C
• Alternative CAS-Nummer: 255730-18-8
• PubChem CID: 11531457
• MeSH-Eintrag: artemisone;BAY 44-9585
• Molekulargewicht: 401.52

Häufig gestellte Fragen

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 255730-18-8, the molecular formula is C19H31NO6S, and the molecular weight is 401.52 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.