AS 101 - 10mM in DMSO , CAS No.106566-58-9

CAS: 106566-58-9 Cat. No.: A420504 Molecular Weight: 312.05 PubChem CID: 24985142

GRADE & PURITY 10mM in DMSO

Synonyms

Ammonium trichloro[1,2-ethanediolato-O,O']-tellurate

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Product introduction

Ossirene (AS101), an immunomodulatory tellurium compound, is a potent IL-1β inhibitor. Ossirene abolishes phosphorylation of STAT3 by inhibiting IL-10. Ossirene potently inhibits Caspase-1 and is used for the autoimmune diseases and certain malignancies.

Specifications

Synonyms

Ammonium trichloro[1, 2-ethanediolato-O, O']-tellurate

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Immunomodulator; inhibits IL-10 synthesis and potentiates IL-1α, IL-2 and TNF-αrelease.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Names and Identifiers

• Canonical Smiles: [Cl-][Te+4]1([Cl-])([O-]CC[O-]1)[Cl-].[NH4+]
• InChIKey: AXWLPMGUUAIGJK-UHFFFAOYSA-O
• Isomeric SMILES: C(C[O-])[O-].[NH4+].[Cl-].[Cl-].[Cl-].[Te+4]
• PubChem CID: 24985142
• Molecular Weight: 312.05