ATWLPPR Peptide TFA, CAS No.A658822

CAS: A658822 Cat. No.: A658822 Molecular Weight: 954

GRADE & PURITY ≥99%

Overview

ATWLPPR Peptide TFA, a heptapeptide, acts as a selective neuropilin-1 inhibitor, inhibits VEGF 165 binding to NRP-1, used in the research of angiogenesis. ATWLPPR Peptide TFA has potential in reducing the early retinal damage caused by diabetes .

Appearance:Solid

IC50& Target:Neuropilin-1

In Vitro:ATWLPPR Peptide TFA is a selective neuropilin-1 inhibitor, inhibits VEGF 165 binding to NRP-1 by 82% at 100 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo:ATWLPPR (400 μg/kg, s.c.) preserves vascular integrity and decreases the oxidative stress level, possibly reduces the early retinal damage caused by diabetes. ATWLPPR prevents the increase of inflammation-associated proteins (GFAP, VEGF and ICAM-1) i

Biological Activity:ATWLPPR Peptide TFA, a heptapeptide, acts as a selective neuropilin-1 inhibitor, inhibits VEGF 165 binding to NRP-1, used in the research of angiogenesis. ATWLPPR Peptide TFA has potential in reducing the early retinal damage caused by diabetes.

Specifications

Product Name

ATWLPPR Peptide TFA, CAS No.A658822

Specifications & Purity

≥99%

Action Type

INHIBITOR

CAS

A658822

Molecule Type

Peptide

Storage and Shipping

Storage

Protected from light,Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs