AurkA allosteric-IN-1 , CAS No.A1426201
Auf Lager
SKU
A1426201
AurkA allosteric-IN-1 (compound 6h) is an Aurora A ( AurkA ) inhibitor ( IC 50 : 6.50 μM) that inhibits the catalytic activity and non-catalytic functions of Aurora A. Aurora A regulates the assembly of the bipolar mitotic spindle and the fidelity of chromosome segregation during mitosis and has non-catalytic functions. AurkA allosteric-IN-1 blocks the interaction of AurkA with the activator TPX2 by binding to the Y pocket of AurkA.
Weitere Informationen
| CAS | A1426201 |
|---|---|
| Storage | Store at -20°C |
| Verschickt in | Ice chest + Ice pads |
| Product Description | AurkA allosteric-IN-1 (compound 6h) is an Aurora A ( AurkA ) inhibitor ( IC 50 : 6.50 μM) that inhibits the catalytic activity and non-catalytic functions of Aurora A. Aurora A regulates the assembly of the bipolar mitotic spindle and the fidelity of chromosome segregation during mitosis and has non-catalytic functions. AurkA allosteric-IN-1 blocks the interaction of AurkA with the activator TPX2 by binding to the Y pocket of AurkA. |
Bewertungen
Kundenbewertungen
Remind me later