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· · COA & SDS available for every product · Same-day shipping on in-stock items AZD4320 - Moligand™ , Inhibitor of BCL2 apoptosis regulator;Inhibitor of Bcl-2-like 1, CAS No.1357576-48-7, Inhibitor of BCL2 apoptosis regulator;Inhibitor of Bcl-2-like 1
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. Synonyms
4-(4-((R)-(4'-chloro-[1,1'-biphenyl]-2-yl)(hydroxy)methyl)piperidin-1-yl)-N-((4-(((R)-4-((2-hydroxyethyl)(methyl)amino)-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)benzamide | Example 3 [US9248140B2] | NSC812728 | NSC-8127
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Why this grade Moligand™ Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Room temperature Ships Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
4-(4-((R)-(4'-chloro-[1, 1'-biphenyl]-2-yl)(hydroxy)methyl)piperidin-1-yl)-N-((4-(((R)-4-((2-hydroxyethyl)(methyl)amino)-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)benzamide | Example 3 [US9248140B2] | NSC812728 | NSC-8127
Specifications & Purity
Moligand™
Mechanism of action
Inhibitor of BCL2 apoptosis regulator;Inhibitor of Bcl-2-like 1
Names and Identifiers Canonical Smiles CN(CCC(CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC(=O)C3=CC=C(C=C3)N4CCC(CC4)C(C5=CC=CC=C5C6=CC=C(C=C6)Cl)O)S(=O)(=O)C(F)(F)F)CCO IUPAC Name 4-[4-[(R)-[2-(4-chlorophenyl)phenyl]-hydroxymethyl]piperidin-1-yl]-N-[4-[[(2R)-4-[2-hydroxyethyl(methyl)amino]-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide InChIKey UNEJSHNDABUZNY-UJNHCCGESA-N INCHI 1S/C45H48ClF3N4O7S3/c1-52(27-28-54)24-23-35(30-61-37-7-3-2-4-8-37)50-41-20-19-38(29-42(41)62(57,58)45(47,48)49)63(59,60)51-44(56)33-13-17-36(18-14-33)53-25-21-32(22-26-53)43(55)40-10-6-5-9-39(40)31-11-15-34(46)16-12-31/h2-20,29,32,35,43,50,54-55H,21-28,30H2,1H3,(H,51,56)/t35-,43-/m1/s1 Isomeric SMILES CN(CC[C@H](CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC(=O)C3=CC=C(C=C3)N4CCC(CC4)[C@H](C5=CC=CC=C5C6=CC=C(C=C6)Cl)O)S(=O)(=O)C(F)(F)F)CCO Alternate CAS 1357576-48-7 PubChem CID 86661883 MeSH Entry Terms 4-(4-((R)-(2-(4-chlorophenyl)phenyl)-hydroxymethyl)piperidin-1-yl)-N-(4-(((2R)-4-(2-hydroxyethyl(methyl)amino)-1-phenylsulfanylbutan-2-yl)amino)-3-(trifluoromethylsulfonyl)phenyl)sulfonylbenzamide;AZD4320
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Class Benzene and substituted derivatives Subclass Biphenyls and derivatives Intermediate Tree Nodes Not available Direct Parent Chlorinated biphenyls Alternative Parents Phenylpiperidines Aminobenzenesulfonamides Aminobenzoic acids and derivatives Benzenesulfonyl compounds Aniline and substituted anilines Thiophenol ethers Benzoyl derivatives Dialkylarylamines Phenylalkylamines Secondary alkylarylamines Chlorobenzenes Alkylarylthioethers Aryl chlorides Organosulfonic acids and derivatives Sulfones Aminosulfonyl compounds Trihalomethanes Secondary alcohols Trialkylamines Amino acids and derivatives 1,2-aminoalcohols Sulfenyl compounds Azacyclic compounds Aromatic alcohols Alkyl fluorides Hydrocarbon derivatives Organic oxides Primary alcohols Organochlorides Organofluorides Organopnictogen compounds Molecular Framework Aromatic heteromonocyclic compounds Substituents Chlorinated biphenyl - Phenylpiperidine - Aminobenzenesulfonamide - Aminobenzoic acid or derivatives - Benzenesulfonamide - Benzoic acid or derivatives - Benzenesulfonyl group - Aryl thioether - Benzoyl - Tertiary aliphatic/aromatic amine - Phenylalkylamine - Aniline or substituted anilines - Dialkylarylamine - Thiophenol ether - Chlorobenzene - Halobenzene - Secondary aliphatic/aromatic amine - Aralkylamine - Alkylarylthioether - Aryl chloride - Aryl halide - Piperidine - Aminosulfonyl compound - Sulfonyl - Organosulfonic acid or derivatives - Organic sulfonic acid or derivatives - Sulfone - Tertiary aliphatic amine - Amino acid or derivatives - Tertiary amine - Trihalomethane - Secondary alcohol - 1,2-aminoalcohol - Organoheterocyclic compound - Sulfenyl compound - Thioether - Azacycle - Secondary amine - Alkanolamine - Carboxylic acid derivative - Hydrocarbon derivative - Alcohol - Primary alcohol - Halomethane - Alkyl halide - Amine - Organic oxide - Organopnictogen compound - Aromatic alcohol - Alkyl fluoride - Organic oxygen compound - Organic nitrogen compound - Organohalogen compound - Organochloride - Organofluoride - Organonitrogen compound - Organooxygen compound - Organosulfur compound - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as chlorinated biphenyls. These are organic compounds containing at least one chlorine atom attached to either benzene ring of the biphenyl moiety. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Molecular Weight 945.500 g/mol XLogP3 9.300 Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 14 Rotatable Bond Count 18 Exact Mass 944.233 Da Monoisotopic Mass 944.233 Da Topological Polar Surface Area 198.000 Ų Heavy Atom Count 63 Formal Charge 0 Complexity 1630.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 2 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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