Azido-PEG4-PFP ester - ≥95% , CAS No.1353012-00-6

CAS: 1353012-00-6 Cat. No.: A595037 Molecular Weight: 457.35 PubChem CID: 60146185
AVAILABLE TO ORDER
GRADE & PURITY ≥95%
Synonyms
N3-PEG4-C2-Pfp ester
Storage
Protected from light,Store at -20°C
Shipped In
Ice chest + Ice pads
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Size
Status
Price
Qty
100mg
A595037-100mg
2
$234.90
250mg
A595037-250mg
2
$497.90
1g
A595037-1g
1
$1,979.90
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Why this grade

≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Azido-PEG4-PFP ester is a PEG derivative containing an azide group and a PFP group. The azide group enables Click Chemistry. The PFP ester is a better leaving group compared to a hydroxyl group and can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer adds to the water solubility of this reagent.

N3-PEG4-C2-Pfp ester is a non-degradable 4-unit PEG linker that can be used to synthesize antiboy-coupled active molecules (ADCs). N3-PEG4-C2-Pfp ester is a click chemical. It contains Azide groups and can undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. Strain-promoted acetylene-azide cycloaddition reactions (SPAAC) can also occur with molecules containing DBCO or BCN groups. 

Application:

Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Specifications

Synonyms
N3-PEG4-C2-Pfp ester
Specifications & Purity
≥95%
Storage
Protected from light, Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥95%
Names and Identifiers
Canonical SmilesC(COCCOCCOCCOCCN=[N+]=[N-])C(=O)OC1=C(C(=C(C(=C1F)F)F)F)F
IUPAC Name(2,3,4,5,6-pentafluorophenyl) 3-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]propanoate
InChIKeyQSIFGTAWLLFXPY-UHFFFAOYSA-N
INCHI1S/C17H20F5N3O6/c18-12-13(19)15(21)17(16(22)14(12)20)31-11(26)1-3-27-5-7-29-9-10-30-8-6-28-4-2-24-25-23/h1-10H2
Isomeric SMILES C(COCCOCCOCCOCCN=[N+]=[N-])C(=O)OC1=C(C(=C(C(=C1F)F)F)F)F
PubChem CID 60146185
Molecular Weight 457.35

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeDateItem
B2427097Certificate of AnalysisJan 20, 2024 A595037
B2427098Certificate of AnalysisJan 20, 2024 A595037
B2427100Certificate of AnalysisJan 20, 2024 A595037
B2427101Certificate of AnalysisJan 20, 2024 A595037
B2427102Certificate of AnalysisJan 20, 2024 A595037
B2427103Certificate of AnalysisJan 20, 2024 A595037
Chemical and Physical Properties
SolubilitySoluble in DMSO, DCM, DMF
SensitivityLight Sensitive
Molecular Weight457.300 g/mol
XLogP32.400
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count13
Rotatable Bond Count17
Exact Mass457.127 Da
Monoisotopic Mass457.127 Da
Topological Polar Surface Area77.600 Ų
Heavy Atom Count31
Formal Charge0
Complexity544.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
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