BAAT Antibody - Primärer Antikörper, specific to BAAT, Rabbit IgG

Cat. No.: Ab090441

GRADE & PURITY Validated, ExactAb™, 1.0 mg/mL

Application

WB

Host species

Kaninchen

Reactive species

Maus, Mensch, Rat

Isotype

Rabbit IgG

Conjugation

Unconjugated

Übersicht

Rabbit anti Human BAAT Antibody, Polyclonal, could be used for WB and so on.
Application:
WB: 1/500-1/2000
Protein Function
Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.

Specifications

Product Name

BAAT Antibody - Primärer Antikörper, specific to BAAT, Rabbit IgG

Synonyme

BAAT antibody | BAAT_HUMAN antibody | BACAT antibody | BAT antibody | Bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase) antibody | Bile acid CoA:amino acid N acyltransferase antibody | Bile acid Coenzyme A amino acid N acyltransfe

Spezifikationen & Reinheit

ExactAb™, Validated, 1.0 mg/mL

Wirtsspezies

Kaninchen

Spezifität

BAAT

Immunogen

A synthetic peptide derived from human BAAT

Positive Kontrolle

WB: A549, A431, HeLa, Jurkat and Hep G2 cell lysates.

Konjugation

Unconjugated

Note

ExactAb™, Validated

Isotyp

Rabbit IgG

SDS-PAGE

150 kDa

Verfahren zur Reinigung

Immunogen affinity purified

Konzentration

1.0 mg/mL

Lagerung und Versand

Form

Liquid

Storage

Store at -20°C,Avoid repeated freezing and thawing

Verschickt in

Ice chest + Ice pads

Stabilität und Lagerung

Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Bilder

Western Blot: BAAT Antibody (Ab090441)

BAAT Antibody (Ab090441) - Western Blot
All lanes: BAAT Antibody (Ab090441) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab176443) at 1/20000 dilution

Predicted band size: 46 kDa
Observed band size: 41 kDa
Exposure time: 5.2 s

Anwendung

• Anwendung: Dilution info
• WB:

  1/500-1/2000;

Zugehörige Ziele (menschlich)

BAAT Tbio Bile acid-CoA:amino acid N-acyltransferase (0 Activities)

Discover Target: BAAT

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)