Benzyl 4-hydroxybenzoate - ≥98% , CAS No.94-18-8

CAS: 94-18-8 Cat. No.: B102189 Molecular Weight: 228.24 Beilstein Registry Number: 2115995 EC Number: 202-311-9
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
EN300-7101475 | BENZYL HYDROXYBENZOATE [WHO-DD] | STL226811 | SY049476 | NCGC00164155-02 | Tox21_302330 | 4-Hydroxybenzoic acid-benzyl ester | Benzyl 4-hydroxybenzoate, 99% | NSC 8080 | Z19674825 | Benzyl Tegosept | Tox21_112088_1 | SMR001600273 | SR-0100
Storage
Room temperature
Shipped In
Normal
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Size
Status
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Qty
5g
B102189-5g
3
$21.90
10g
B102189-10g
1
$31.90
25g
B102189-25g
4
$62.90
100g
B102189-100g
1
$220.90
250g
B102189-250g
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$546.90
500g
B102189-500g
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 4 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Benzyl Paraben is an anti-microbial
It may be used as internal standard for the simultaneous analysis of non-steroidal anti-inflammatory drugs in human plasma and urine using microextraction by packed sorbent and HPLC method;And it may be employed as internal standard for the HPLC determination of rutin, kaempferol, genistein, formononetin and biochanin A in Ononis spinosu roots.

Specifications

Synonyms
EN300-7101475 | BENZYL HYDROXYBENZOATE [WHO-DD] | STL226811 | SY049476 | NCGC00164155-02 | Tox21_302330 | 4-Hydroxybenzoic acid-benzyl ester | Benzyl 4-hydroxybenzoate, 99% | NSC 8080 | Z19674825 | Benzyl Tegosept | Tox21_112088_1 | SMR001600273 | SR-0100
Specifications & Purity
≥98%
Storage
Room temperature
Shipped In
Normal
Purity
≥98%
Names and Identifiers
Pubchem Sid488180325
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488180325
Canonical SmilesC1=CC=C(C=C1)COC(=O)C2=CC=C(C=C2)O
IUPAC Namebenzyl 4-hydroxybenzoate
InChIKeyMOZDKDIOPSPTBH-UHFFFAOYSA-N
INCHI1S/C14H12O3/c15-13-8-6-12(7-9-13)14(16)17-10-11-4-2-1-3-5-11/h1-9,15H,10H2
Isomeric SMILES C1=CC=C(C=C1)COC(=O)C2=CC=C(C=C2)O
WGK Germany 3
RTECS DH2691000
UN Number 3077
Molecular Weight 228.24
Beilstein 2115995
Reaxy-Rn 2115995
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2115995&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassBenzene and substituted derivatives
SubclassBenzoic acids and derivatives
Intermediate Tree Nodes Benzoic acid esters - p-Hydroxybenzoic acid esters
Direct Parentp-Hydroxybenzoic acid alkyl esters
Alternative Parents Benzyloxycarbonyls  Benzoyl derivatives  1-hydroxy-2-unsubstituted benzenoids  Carboxylic acid esters  Monocarboxylic acids and derivatives  Organooxygen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents P-hydroxybenzoic acid alkyl ester - Benzyloxycarbonyl - Benzoyl - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Carboxylic acid ester - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as p-hydroxybenzoic acid alkyl esters. These are aromatic compounds containing a benzoic acid, which is esterified with an alkyl group and para-substituted with a hydroxyl group.
External Descriptors benzoate ester
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LMNA Tbio Prelamin-A/C (36751 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PMP22 Tbio Peripheral myelin protein 22 (699 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Dermatophagoides pteronyssinus (58 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Luciferin 4-monooxygenase (66902 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

14 results found

Lot NumberCertificate TypeDateItem
C2624153Certificate of AnalysisApr 02, 2026 B102189
B23021124Certificate of AnalysisFeb 11, 2023 B102189
B23021148Certificate of AnalysisFeb 11, 2023 B102189
B23021149Certificate of AnalysisFeb 11, 2023 B102189
B23021184Certificate of AnalysisFeb 11, 2023 B102189
B23021189Certificate of AnalysisFeb 11, 2023 B102189
B23021197Certificate of AnalysisFeb 11, 2023 B102189
C2531040Certificate of AnalysisFeb 11, 2023 B102189
E2324048Certificate of AnalysisFeb 11, 2023 B102189
B2302519Certificate of AnalysisFeb 07, 2023 B102189
B2302520Certificate of AnalysisFeb 07, 2023 B102189
B2302522Certificate of AnalysisFeb 07, 2023 B102189
B2302523Certificate of AnalysisFeb 07, 2023 B102189
B2302524Certificate of AnalysisFeb 07, 2023 B102189

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Chemical and Physical Properties
SolubilitySoluble in Methanol
Melt Point(°C)109-112°C
Molecular Weight228.240 g/mol
XLogP33.600
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass228.079 Da
Monoisotopic Mass228.079 Da
Topological Polar Surface Area46.500 Ų
Heavy Atom Count17
Formal Charge0
Complexity238.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Li Shuo, Jia Mengtian, Guo Hongqiao, Hou Xiaohong.  (2018)  Development and application of metal organic framework/chitosan foams based on ultrasound-assisted solid-phase extraction coupling to UPLC-MS/MS for the determination of five parabens in water.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  410  (25): (6619-6632).  [PMID:30062509] [10.1007/s00216-018-1269-2]
2. Hang Ning, Wen-long Liu, Qing-yun Li, You-yan Liu, Shi-ting Huang, Hai-bo Liu, Ai-xing Tang.  (2024)  Substrate Characterization for Hydrolysis of Multiple Types of Aromatic Esters by Promiscuous Aminopeptidases.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:39021280] [10.1021/acs.jafc.4c02053]
3. Bingbing Yuan, Shuang Yuan, Chaozheng Jia, Ping Hu, Siheng Zhao, Xiaozhuan Zhang, Zewen Xu, Lihong Liu, Meng You, Shengchao Zhao, Kuo Chen, Dongxiao Yang, Juhui Jiang, Xiangdong Lou, Jianxun Dong, Tatiana V. Plisko, Q.Jason Niu.  (2025)  ZIF-8 ligand exchange-driven fabrication of high-permeability reverse osmosis membranes for desalination and small molecule pollutant removal.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2025.134457]
4. Yidong Zhou, Zhijian Ke, Jiazhuo Zhang, Wenbin Chang, Yarong Cui, Yimiao Chen, Yirui Huang, Chunli Xia, Wenjia Zhong, Zifa Deng, Dayong Jin.  (2025)  The strategy of transesterification and degradation improved the resistance of Microbacterium sp. S1037 to antiseptic parabens.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:40446366] [10.1016/j.jhazmat.2025.138751]
Solution Calculators
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