BIO5192 hydrate - 10mM in DMSO , CAS No.B661664(DMSO)

CAS: B661664(DMSO) Cat. No.: B661664 Molecular Weight: 826.79
AVAILABLE TO ORDER
GRADE & PURITY 10mM in DMSO
Storage
Desiccated,Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1ml
B661664-1ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$484.90
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Desiccated,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

BIO5192 hydrate is a selective and potent integrin α4β1 (VLA-4) inhibitor ( K d <10 pM). BIO5192 hydrate selectively binds to α4β1 ( IC 50 =1.8 nM) over a range of other integrins. BIO5192 hydrate results in a 30-fold increase in mobilization of murine he

IC50& Target:α4β1 1.8 nM (IC 50 ) α9β1 138 nM (IC 50 ) α2β1 1053 nM (IC 50 ) α4β7 >500 nM (IC 50 )

In Vivo:The combination of BIO5192 hydrate (1mg/kg; i.v.) and Plerixafor (5mg/kg; s.c.) exert an additive effect on progenitor mobilization. BIO5192 hydrate (30mg/kg; s.c; bid; during days 5 through 14) delays paralysis associated with EAE (experimental a

Biological Activity:BIO5192 hydrate is a selective and potent integrin α4β1 (VLA-4) inhibitor ( K d <10 pM). BIO5192 hydrate selectively binds to α4β1 ( IC 50 =1.8 nM) over a range of other integrins. BIO5192 hydrate results in a 30-fold increase in mobilization of murine he

Specifications

Specifications & Purity
10mM in DMSO
Storage
Desiccated, Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Names and Identifiers
Molecular Weight 826.79

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Solution Calculators
Reviews

Customer Reviews

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