Bobcat339 hydrochloride - 10mM in DMSO , CAS No.2436747-44-1

CAS: 2436747-44-1 Cat. No.: B656698 Summenformel: C₁₆H₁₃Cl₂N₃O Molekulargewicht: 334.20 PubChem CID: 138319672

GRADE & PURITY 10mM in DMSO

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

Bobcat339 hydrochloride is a potent and selective cytosine-based inhibitor of TET enzyme , with the IC 50 s of 33 μM and 73 μM for TET1 and TET2 , respectively. Bobcat339 hydrochloride is useful to the field of epigenetics and serves as a starting point for new therapeutics that target DNA methylation and gene transcription

In Vitro

Bobcat339 (10 μM; 24 hours) significantly reduces global 5hmC levels by inhibiting TET enzyme function in HT-22 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:TET1 33 μM (IC 50 ) TET2 73 μM (IC 50 )

Specifications

Spezifikationen & Reinheit

10mM in DMSO

Biochemische und physiologische Mechanismen

Bobcat339 hydrochloride is a potent and selective cytosine-based inhibitor of TET enzyme , with the IC 50 s of 33 μM and 73 μM for TET1 and TET2 , respectively. Bobcat339 hydrochloride is useful to the field of epigenetics and serves as a starting point f

Storage

Desiccated,Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

INHIBITOR

Namen und Kennungen

• PubChem CID: 138319672
• Molekulargewicht: 334.20