bpV(HOpic) - ≥95% , CAS No.722494-26-0

CAS: 722494-26-0 Cat. No.: B334661 Summenformel: C₆H₄K₂NO₈V Molekulargewicht: 347.24 EG-Nummer: 806-224-2 PubChem CID: 54692867

GRADE & PURITY ≥95%

Synonyms

Dipotassium bisperoxo (5-hydroxypyridine-2-carboxyl) oxovanadate (V) | Bisperoxovanadium(HOpic) | (5-hydroxy-2-pyridinecarboxylato-κN1,κO2)oxodiperoxy-vanadate(2-), dipotassium

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Übersicht

bpV(HOpic) is a bisperoxo oxovanadate dipotassium salt coordinated to 5-hydroxypyridine-2-carboxylate. This vanadium compound has been shown to be a potent inhibitor of protein phosphotyrosine phosphatase (PTP) and PTEN, and has been described to act as an insulin mimetic. This compound has been shown to activate the insulin receptor kinase of hepatoma cells, stimulate lipogenesis in adipocytes, and to enhance PI3K/Akt signaling that could prevent ischemia-reperfusion (I/R) injury to the myocardium.

Specifications

Synonyme

Dipotassium bisperoxo (5-hydroxypyridine-2-carboxyl) oxovanadate (V) | Bisperoxovanadium(HOpic) | (5-hydroxy-2-pyridinecarboxylato-κN1,κO2)oxodiperoxy-vanadate(2-), dipotassium

Spezifikationen & Reinheit

≥95%

Biochemische und physiologische Mechanismen

bpV(OHpic) is a bisperoxovanadium inhibitor of protein phosphotyrosine phosphatases with selectivity for PTEN, phosphatase and tensin homolog, a tumour suppressor phosphatase involved in cell cycle regulation. IC50 values for bpV(HOpic) are 14 nM for PTEN

Storage

Protected from light,Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Reinheit

≥95%

Namen und Kennungen

Isomere SMILES

C1=CC(=NC=C1[O-])C(=O)O.OO.OO.O=[V].[K+].[K+]

WGK Deutschland

3

PubChem CID

54692867

Molekulargewicht

347.24

Chemische und physikalische Eigenschaften

• Löslichkeit: Soluble in cold water (easily), and DMSO. Note: This product is not stable in water. Starts decomposition immediately after solubilization. Rate of decomposition is slower in dry DMSO.
• Empfindlichkeit: Light & Moisture sensitive

Häufig gestellte Fragen

What is the purity of this product?

This product is supplied at ≥95% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C, protected from light. The material is light-sensitive — keep it in its original opaque or amber container.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 722494-26-0, the molecular formula is C6H4K2NO8V, and the molecular weight is 347.24 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.