Braftide - ≥99% , CAS No.2411851-64-2

CAS: 2411851-64-2 Cat. No.: B1436498 Summenformel: C₅₇H₉₄N₁₆O₁₃S Molekulargewicht: 1243.52

GRADE & PURITY ≥99%

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

Braftide is an allosteric inhibitor for BRAF kinase by targeting the dimer interface of BRAF kinase and inhibiting the formation of BRAF dimers. Braftide inhibits wild-type BRAF and oncogenic BRAF G469A with IC 50 of 364 nM and 172 nM, respectively. Braftide inhibits MAPK signaling pathway, inhibits proliferation of KRAS mutant tumor cells ( EC 50 is 7.1 and 6.6 μM, for HCT116 and HCT-15), in combination of TAT sequence.

Specifications

Spezifikationen & Reinheit

≥99%

Storage

Desiccated,Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

INHIBITOR

Reinheit

≥99%

Namen und Kennungen

• Molekulargewicht: 1243.52