≥99%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C,Desiccated Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Product description：
C-021 dihydrochloride is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C-021 dihydrochloride effectively prevents human CCL22-derived [35S]GTPγS from binding to the receptor with an IC50 of 18 nM.
| Pubchem Sid | 488201805 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488201805 |
| Kanonisches Lächeln | COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCC(CC3)N4CCCCC4)NC5CCCCCC5)OC.Cl.Cl |
| IUPAC Name | N-cycloheptyl-6,7-dimethoxy-2-(4-piperidin-1-ylpiperidin-1-yl)quinazolin-4-amine;dihydrochloride |
| InChIKey | GKJKNYQUFAPLOQ-UHFFFAOYSA-N |
| INCHI | 1S/C27H41N5O2.2ClH/c1-33-24-18-22-23(19-25(24)34-2)29-27(30-26(22)28-20-10-6-3-4-7-11-20)32-16-12-21(13-17-32)31-14-8-5-9-15-31;;/h18-21H,3-17H2,1-2H3,(H,28,29,30);2*1H |
| Isomere SMILES | COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCC(CC3)N4CCCCC4)NC5CCCCCC5)OC.Cl.Cl |
| PubChem CID | 56972238 |
| Molekulargewicht | 540.57 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Klasse | Diazanaphthalenes |
| Subclass | Benzodiazines |
| Intermediate Tree Nodes | Quinazolines |
| Direct Parent | Quinazolinamines |
| Alternative Parents | Dialkylarylamines Anisoles Aminopyrimidines and derivatives Aminopiperidines Alkyl aryl ethers Imidolactams Heteroaromatic compounds Trialkylamines Azacyclic compounds Hydrochlorides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Quinazolinamine - Anisole - Phenol ether - Dialkylarylamine - Alkyl aryl ether - 4-aminopiperidine - Aminopyrimidine - Imidolactam - Benzenoid - Pyrimidine - Piperidine - Heteroaromatic compound - Tertiary aliphatic amine - Tertiary amine - Azacycle - Ether - Organonitrogen compound - Amine - Organic nitrogen compound - Hydrocarbon derivative - Organic oxygen compound - Organooxygen compound - Hydrochloride - Aromatic heteropolycyclic compound |
| Beschreibung | This compound belongs to the class of organic compounds known as quinazolinamines. These are heterocyclic aromatic compounds containing a quianazoline moiety substituted by one or more amine groups. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Datum | Artikel |
|---|---|---|---|
 E23181048 | Certificate of Analysis | Mar 10, 2026 | C288233 |
| E23181052 | Certificate of Analysis | Mar 10, 2026 | C288233 |
| E23181057 | Certificate of Analysis | Mar 10, 2026 | C288233 |
| E23181060 | Certificate of Analysis | Mar 10, 2026 | C288233 |
| E23181063 | Certificate of Analysis | Mar 10, 2026 | C288233 |
| E23181065 | Certificate of Analysis | Mar 10, 2026 | C288233 |
| E23181066 | Certificate of Analysis | Mar 10, 2026 | C288233 |
| E23181069 | Certificate of Analysis | Mar 10, 2026 | C288233 |
| E23181071 | Certificate of Analysis | Mar 10, 2026 | C288233 |
| E23181074 | Certificate of Analysis | Mar 10, 2026 | C288233 |
| Löslichkeit | Solvent:water, Max Conc. mg/mL: 26.96, Max Conc. mM: 50; Solvent:DMSO, Max Conc. mg/mL: 53.93, Max Conc. mM: 100 |
|---|---|
| Empfindlichkeit | Moisture sensitive |
| Molekulargewicht | 540.600 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 6 |
| Exact Mass | 539.279 Da |
| Monoisotopic Mass | 539.279 Da |
| Topological Polar Surface Area | 62.800 Ų |
| Heavy Atom Count | 36 |
| Formal Charge | 0 |
| Complexity | 602.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 3 |
