Carboplatin - Moligand™, 10mM in Water , CAS No.41575-94-4
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SKU
C423884
Antitumor agent; blocks DNA replication and transcription. Cisplatin analog.
Product Description
Carboplatin is believed to form inter- and intrastrand DNA adducts which activate signaling pathways culminating in apoptosis. The development of carboplatin was inspired from the efficacy of its progenitor, Cisplatin (sc-200896), the first of this class of antineoplastic agents. The action of this group of platinum-based compounds is primarily attributed to DNA adduct formation, however, these molecules also bind other biological molecules, including enzymes, which might play a role in their mechanism of action.
An antitumor agent that binds to DNA leading to apoptosis
Product Application
Carboplatin has been used:
in chemotherapy-induced thrombocytopenia mouse model and treatment
to induce cell death in a large subset of colorectal cancer cells
in the evaluation of cell proliferation and chemosensitivity
as a positive control for suppressed cell growth
Product class
hAPIs, Metal based hAPIs
Chemical properties
Chemical formula
C6H12N2O4Pt
Empirical formula
[Pt(NH3)2(cbdc)]
Molecular weight
371.25
Metal
Pt
Theoretical metal content
53
Physical state
powder
Color
white
Weitere Informationen
| CAS | 41575-94-4 |
|---|---|
| Konzentration | 10mM in Water |
| Synonyme | 41575-94-4|Carboplatin|Paraplatin|Cbdca|Carboplatinum|MFCD00070464|NSC-241240|cis-(1,1-Cyclobutanedicarboxylato)diammineplatinum(II)|cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II)|1,1-Cyclobutanedicarboxylate diammine platinum(II)|cis-Diammine(1,1 |
| Spezifikationen & Reinheit | Moligand™, 10mM in Water |
| Storage | Protected from light,Store at -80°C |
| Verschickt in | Dry ice packs + Cold packs |
| Product Description | Product Description Product Application as a positive control for suppressed cell growth Product class Chemical properties Chemical formula C6H12N2O4Pt Empirical formula [Pt(NH3)2(cbdc)] Molecular weight 371.25 Metal Pt Theoretical metal content 53 Physical state powder Color white |
| Pubchem Sid | 528770346 |
| Empfindlichkeit | Light sensitive. |
| EG-Nummer | 255-446-0 |
| PubChem CID | 426756 |
| Molekulare Formel | C6H12N2O4Pt |
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