Cardamonin - ≥98% , CAS No.19309-14-9

Name: Cardamonin - ≥98% , CAS No.19309-14-9
Brand: Aladdin Scientific
SKU: C275625
Availability: InStock

CAS: 19309-14-9 Cat. No.: C275625 Summenformel: C₁₆H₁₄O₄ Molekulargewicht: 270.28 EG-Nummer: 663-565-8

7 Citations COA

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Cardamonin - ≥98% CAS No(19309-14-9) by Aladdin Scientific

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QUALITÄT & REINHEIT ≥98%

Synonyms

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

Übersicht Spezifikationen Namen und Kennungen Dokumentation Erweiterte Daten Taxonomic Classification 3D-Struktur Zugehörige Ziele (menschlich) Zugehörige Ziele (nicht menschlich) Wirkungsmechanismen Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm) Chemische und physikalische Eigenschaften FAQs und Artikel Citations of This Product Lösungsrechner Bewertungen

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Warum diese Qualität

≥98% für empfindliche chromatographische und analytische Workflows, die minimale Basislinieninterferenzen erfordern.

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Lagerung & Versand

Store at 2-8°C,Desiccated Versand Wet ice. Genaue Spezifikationen finden Sie im chargenspezifischen COA.

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Qualitätsdokumente

SDS, COA, Datenblatt und Spezifikationsblatt stehen zum Download bereit. Chargenspezifische COA über Chargennummernsuche abrufbar.

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Literaturbeleg

In 7 peer-reviewten Publikationen zu Chromatographie, organischer Synthese und Kreuzkupplungsreaktionen zitiert.

Übersicht

Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Spezifikationen

Synonyme

Spezifikationen & Reinheit

≥98%

Biochemische und physiologische Mechanismen

Anticancer, anti-inflammatory spice-derived chalcone analog. Shown to supress numerous signaling pathways including TNF-α, COX-2, Wnt/β-catenin and NF-κB.

Storage

Store at 2-8°C,Desiccated

Verschickt in

Wet ice

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

ANTAGONIST

Hinweis

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Reinheit

≥98%

Namen und Kennungen

Pubchem Sid

508813323

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/508813323

Kanonisches Lächeln

COC1=CC(=CC(=C1C(=O)C=CC2=CC=CC=C2)O)O

IUPAC Name

(E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one

InChIKey

NYSZJNUIVUBQMM-BQYQJAHWSA-N

INCHI

1S/C16H14O4/c1-20-15-10-12(17)9-14(19)16(15)13(18)8-7-11-5-3-2-4-6-11/h2-10,17,19H,1H3/b8-7+

Isomere SMILES

COC1=CC(=CC(=C1C(=O)/C=C/C2=CC=CC=C2)O)O

Molekulargewicht

270.28

Reaxy-Rn

1990785

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1990785&ln=

Dokumentation

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✅ Analysezertifikat (COA)

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Erweiterte Daten

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Phenylpropanoids and polyketides
  - Klasse Linear 1,3-diarylpropanoids
    - Subclass Chalcones and dihydrochalcones

Kingdom	Organic compounds
Superclass	Phenylpropanoids and polyketides
Klasse	Linear 1,3-diarylpropanoids
Subclass	Chalcones and dihydrochalcones
Intermediate Tree Nodes	Not available
Direct Parent	2'-Hydroxychalcones
Alternative Parents	Cinnamylphenols Methoxyphenols Styrenes Resorcinols Phenoxy compounds Methoxybenzenes Anisoles Benzoyl derivatives Aryl ketones 1-hydroxy-2-unsubstituted benzenoids 1-hydroxy-4-unsubstituted benzenoids Alkyl aryl ethers Vinylogous acids Acryloyl compounds Enones Hydrocarbon derivatives Organic oxides
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	2'-hydroxychalcone - Cinnamylphenol - Methoxyphenol - Anisole - Benzoyl - Phenoxy compound - Phenol ether - Resorcinol - Styrene - Aryl ketone - Methoxybenzene - 1-hydroxy-2-unsubstituted benzenoid - 1-hydroxy-4-unsubstituted benzenoid - Alkyl aryl ether - Phenol - Monocyclic benzene moiety - Benzenoid - Vinylogous acid - Alpha,beta-unsaturated ketone - Enone - Acryloyl-group - Ketone - Ether - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Organooxygen compound - Aromatic homomonocyclic compound
Beschreibung	This compound belongs to the class of organic compounds known as 2'-hydroxychalcones. These are organic compounds containing chalcone skeleton that carries a hydroxyl group at the 2'-position.
External Descriptors	Chalcones and dihydrochalcones
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D-Struktur

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KCNA3 Tclin Potassium voltage-gated channel subfamily A member 3 (2 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTH1R Tclin Parathyroid hormone receptor (47172 Activities)

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KCNA3 Tclin Voltage-gated potassium channel subunit Kv1.3 (1067 Activities)

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MAPK9 Tchem c-Jun N-terminal kinase 2 (4655 Activities)

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MAPK8 Tchem c-Jun N-terminal kinase 1 (5038 Activities)

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AGS (1999 Activities)

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CCRF-CEM (65223 Activities)

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DLD-1 (17511 Activities)

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PANC-1 (6144 Activities)

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HCT-116 (91556 Activities)

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HepG2 (196354 Activities)

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GNAS Tbio Guanine nucleotide-binding protein G(s), subunit alpha (103405 Activities)

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POLI Tchem DNA polymerase iota (116820 Activities)

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KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

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TNFRSF10B Tbio Tumor necrosis factor receptor superfamily member 10B (15 Activities)

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SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 Activities)

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GMNN Tbio Geminin (128009 Activities)

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APOBEC3G Tchem DNA dC->dU-editing enzyme APOBEC-3G (12481 Activities)

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BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 Activities)

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ATXN2 Tbio Ataxin-2 (54410 Activities)

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RAPGEF3 Tchem Rap guanine nucleotide exchange factor 3 (15528 Activities)

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MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)

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Plasmodium falciparum (966862 Activities)

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Leishmania amazonensis (3813 Activities)

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Schistosoma mansoni (6170 Activities)

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RAW264.7 (28094 Activities)

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Dengue virus type 2 NS3 protein (2214 Activities)

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Npsr1 Neuropeptide S receptor (260 Activities)

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Luciferin 4-monooxygenase (66902 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

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Protease (18 Activities)

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TGR Thioredoxin glutathione reductase (28579 Activities)

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Mapt Microtubule-associated protein tau (6 Activities)

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Rorc Nuclear receptor ROR-gamma (89407 Activities)

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vpr Aberrant vpr protein (14595 Activities)

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SARS-CoV-2 (38078 Activities)

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Wirkungsmechanismen

Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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5 results found

Lot Number	Certificate Type	Datum	Artikel
F2220283	Certificate of Analysis	Apr 03, 2026	C275625
F2220284	Certificate of Analysis	Apr 03, 2026	C275625
F2220352	Certificate of Analysis	Apr 03, 2026	C275625
F2220353	Certificate of Analysis	Apr 03, 2026	C275625
F2220354	Certificate of Analysis	Jun 01, 2022	C275625

Chemische und physikalische Eigenschaften

Löslichkeit	Soluble in DMSO to 100 mM and in ethanol to 25 mM
Molekulargewicht	270.280 g/mol
XLogP3	3.500
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	4
Exact Mass	270.089 Da
Monoisotopic Mass	270.089 Da
Topological Polar Surface Area	66.800 Å²
Heavy Atom Count	20
Formal Charge	0
Complexity	346.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	1
Covalently-Bonded Unit Count	1

FAQs und Artikel

RNA Viruses Triggered Signal Pathway

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

NF-kB signaling pathway Signaling pathway RNA virus NF-kB

Citations of This Product

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Lösungsrechner

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📚 Zitationen nach Anwendung

Organic synthesis — reaction medium5

Drug / compound screening1

Cytotoxicity screening1

Extraction & workup solvent4

Crystallization & recrystallization1

Other applications2

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Cardamonin - ≥98% , CAS No.19309-14-9

Lagerung & Versand

Qualitätsdokumente

Literaturbeleg

Übersicht

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Dokumentation

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