CBWD2 Antibody - Primärer Antikörper, specific to ZNG1B, Rabbit IgG

Cat. No.: Ab093328

GRADE & PURITY Validated, ExactAb™, 1.0 mg/mL

Application

WB

Host species

Kaninchen

Reactive species

Maus, Mensch, Rat

Isotype

Rabbit IgG

Conjugation

Unconjugated

Übersicht

Rabbit anti Human CBWD2 Antibody, Polyclonal, could be used for WB and so on.
Application:
WB: 1/500-1/2000
Protein Function
Zinc chaperone that directly transfers zinc cofactor to target metalloproteins, thereby activating them. Catalyzes zinc insertion into the active site of methionine aminopeptidase METAP1, which function to cleave the initiator methionine from polypeptides during or after protein translation. Mechanistically, the N-terminal psi-PxLVp motif binds to the C6H2-type zinc finger of inactive form of METAP1. After formation of the docked complex, zinc is transferred from the CXCC motif in the GTPase domain of ZNG1B to the zinc binding site in the peptidase domain of METAP1 in a process requiring GTP hydrolysis. GTP/GDP exchange is required for release of active METAP1.

Specifications

Product Name

CBWD2 Antibody - Primärer Antikörper, specific to ZNG1B, Rabbit IgG

Synonyme

CBWD2_HUMAN antibody | Cobalamin synthase W domain-containing protein 2 antibody | Cobalamin synthetase W domain-containing protein 2 antibody | COBW domain-containing protein 2 antibody | ZNG1B | CBWD2 | CBWD2 antibody

Spezifikationen & Reinheit

ExactAb™, Validated, 1.0 mg/mL

Wirtsspezies

Kaninchen

Spezifität

ZNG1B

Immunogen

A synthetic peptide derived from human CBWD2 (AA 108-158)

Positive Kontrolle

WB: Rat lung, U-2 OS, HeLa and THP-1 lysates.

Konjugation

Unconjugated

Note

ExactAb™, Validated

Isotyp

Rabbit IgG

SDS-PAGE

150 kDa

Verfahren zur Reinigung

Immunogen affinity purified

Konzentration

1.0 mg/mL

Lagerung und Versand

Form

Liquid

Storage

Store at -20°C,Avoid repeated freezing and thawing

Verschickt in

Ice chest + Ice pads

Stabilität und Lagerung

Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Bilder

Western Blot: CBWD2 Antibody (Ab093328)

CBWD2 Antibody (Ab093328) - Western Blot
All lanes: CBWD2 Antibody (Ab093328) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 43 kDa
Observed band size: 42 kDa
Exposure time: 30.0 s

Anwendung

• Anwendung: Dilution info
• WB:

  1/500-1/2000 ;