CCR6 inhibitor 1 - 10mM in DMSO , CAS No.2437547-04-9

CAS: 2437547-04-9 Cat. No.: C656274 Summenformel: C₂₄H₂₃F₃N₄O₃S Molekulargewicht: 504.52

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

CCR6 inhibitor 1 is a potent and selective CCR6 inhibitor, with IC 50 s of 0.45 and 6 nM for monkey and human CCR6 , much more selective at CCR6 over human CCR1 (IC 50 , > 30000 nM), and CCR7 (IC 50 , 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancer

In Vitro

CCR6 inhibitor 1 (Compound 35) inhibits L20-induced human B cell migration. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:Moneky CCR6 0.45 nM (IC 50 ) Human CCR6 6 nM (IC 50 ) Human CCR7 9400 nM (IC 50 )

Specifications

Spezifikationen & Reinheit

10mM in DMSO

Biochemische und physiologische Mechanismen

CCR6 inhibitor 1 is a potent and selective CCR6 inhibitor, with IC 50 s of 0.45 and 6 nM for monkey and human CCR6 , much more selective at CCR6 over human CCR1 (IC 50 , > 30000 nM), and CCR7 (IC 50 , 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phospho

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

INHIBITOR

Namen und Kennungen

Molekulargewicht

504.52