CCT007093 - 2mM in DMSO , CAS No.176957-55-4

Name: CCT007093 - 2mM in DMSO , CAS No.176957-55-4
SKU: C422158
Availability: InStock

CAS: 176957-55-4 Cat. No.: C422158 Summenformel: C₁₅H₁₂OS₂ Molekulargewicht: 272.39 EG-Nummer: 631-499-9

COA

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CCT007093 - 2mM in DMSO CAS No(176957-55-4) by Aladdin Scientific

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GRADE & PURITY 2mM in DMSO

Synonyms

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht Specifications Namen und Kennungen Documentation Advanced Data Taxonomic Classification 3D-Struktur Zugehörige Ziele (menschlich) Zugehörige Ziele (nicht menschlich) Wirkungsmechanismen Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm) Chemische und physikalische Eigenschaften Lösungsrechner Bewertungen

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Why this grade

2mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Übersicht

CCT007093 is an effective PPM1D inhibitor that selectively reduces viability of human tumour cell lines. PPM1D is a phosphatase where the gene which is aberrantly amplified in a range of common cancers. PPM1D activation results in negative regulation of P53 function by selective inactivation of P38 kinase. Therefore, this enzyme can be considered as a potential therapeutic target for cancer. The present study identified a compound, CCT007093 that selectively reduces viability of human tumour cell lines overexpressing PPM1D through inhibition of this phosphatase. The unique advantage of CCT007093 is its ability to mimic the effects of gene-specific PPM1D RNAi, both in its selectivity for human tumour cells that overexpress PPM1D and also by its reliance on an integral P38 pathway.

Specifications

Synonyme

Spezifikationen & Reinheit

2mM in DMSO

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

ACTIVATOR

Namen und Kennungen

Kanonisches Lächeln	C1CC(=CC2=CC=CS2)C(=O)C1=CC3=CC=CS3
IUPAC Name	(2E,5E)-2,5-bis(thiophen-2-ylmethylidene)cyclopentan-1-one
InChIKey	KPFZCKDPBMGECB-WGDLNXRISA-N
INCHI	1S/C15H12OS2/c16-15-11(9-13-3-1-7-17-13)5-6-12(15)10-14-4-2-8-18-14/h1-4,7-10H,5-6H2/b11-9+,12-10+
Isomere SMILES	C1/C(=C\C2=CC=CS2)/C(=O)/C(=C/C3=CC=CS3)/C1
Molekulargewicht	272.39
Reaxy-Rn	23977527
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=23977527&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Klasse Heteroaromatic compounds

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Klasse	Heteroaromatic compounds
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Heteroaromatic compounds
Alternative Parents	Thiophenes Cyclic ketones Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Heteroaromatic compound - Thiophene - Cyclic ketone - Ketone - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aromatic heteromonocyclic compound
Beschreibung	This compound belongs to the class of organic compounds known as heteroaromatic compounds. These are compounds containing an aromatic ring where a carbon atom is linked to an hetero atom.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D-Struktur

Zugehörige Ziele (menschlich)

5637 (630 Activities)

Molekulargewicht	272.400 g/mol
XLogP3	4.000
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	2
Exact Mass	272.033 Da
Monoisotopic Mass	272.033 Da
Topological Polar Surface Area	73.600 Å²
Heavy Atom Count	18
Formal Charge	0
Complexity	361.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	2
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	2
Covalently-Bonded Unit Count	1