Cedirogant - ≥99% , CAS No.2055496-11-0

CAS: 2055496-11-0 Cat. No.: C651724 Summenformel: C₂₄H₂₀Cl₃F₃N₂O₃ Molekulargewicht: 547.78 PubChem CID: 124123797

QUALITÄT & REINHEIT ≥99%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Übersicht

Cedirogant (ABBV-157) is an orally active RORγt inverse agonist. Cedirogant can be used for psoriasis research

In Vitro

The transcription factor retinoic acid-related orphan receptor gamma t (RORγt) has been identified as the master regulator of TH17 cell differentiation and IL-17/22 production and is therefore an attractive target for the treatment of inflammatory diseases. Cedirogant (ABBV-157) has the potential for chronic plaque psoriasis research. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:RORγt

Spezifikationen

Spezifikationen & Reinheit

≥99%

Biochemische und physiologische Mechanismen

Cedirogant (ABBV-157) is an orally active RORγt inverse agonist. Cedirogant can be used for psoriasis research.

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

INHIBITOR

Reinheit

≥99%

Namen und Kennungen

Isomere SMILES

C1CN(CCC1CC(=O)O)C(=O)C2=C(C(=C(C=C2)Cl)CN3C=CC4=CC(=CC(=C43)Cl)C(F)(F)F)Cl

PubChem CID

124123797

Molekulargewicht

547.78

Chemische und physikalische Eigenschaften

• Löslichkeit: DMSO : 250 mg/mL (456.39 mM; Need ultrasonic)
• Molekulargewicht: 547.800 g/mol
• XLogP3: 6.100
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 546.049 Da
• Monoisotopic Mass: 546.049 Da
• Topological Polar Surface Area: 62.500 Ų
• Heavy Atom Count: 35
• Formal Charge: 0
• Complexity: 781.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1