Ceftaroline Fosamil - Moligand™, ≥98% , CAS No.400827-46-5

CAS: 400827-46-5 Cat. No.: C413097 Summenformel: C₂₄H₂₅N₈O₁₀PS₄ Molekulargewicht: 744.74 EG-Nummer: 805-487-0

GRADE & PURITY Moligand™, ≥98%

Synonyms

UNII-EZ9W6O5S09 | Ceftaroline fosamil acetate anhydrous | Ceftaroline fosamil | DTXSID50193133 | EZ9W6O5S09 | TAK 599 | Teflaro | Zinforo | PPI 0903 | Pyridinium, 4-(2-(((6R,7R)-2-carboxy-7-(((2Z)-(ethoxyimino)(5-(phosphonoamino)-1,2,4-thiadiazol-3-yl)ace

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Übersicht

Information

Ceftaroline Fosamil Ceftaroline fosamil (CX-0903, DSP-5990, PPI-0903, TAK-599, Teflaro, Zinforo) is a cephalosporin with activity against Gram-positive pathogens , including methicillin-resistant Staphylococcus aureus (MRSA).

Specifications

Synonyme

UNII-EZ9W6O5S09 | Ceftaroline fosamil acetate anhydrous | Ceftaroline fosamil | DTXSID50193133 | EZ9W6O5S09 | TAK 599 | Teflaro | Zinforo | PPI 0903 | Pyridinium, 4-(2-(((6R,7R)-2-carboxy-7-(((2Z)-(ethoxyimino)(5-(phosphonoamino)-1,2,4-thiadiazol-3-yl)ace

Spezifikationen & Reinheit

Moligand™, ≥98%

Biochemische und physiologische Mechanismen

Ceftaroline fosamil (CX-0903, DSP-5990, PPI-0903, TAK-599, Teflaro, Zinforo) is a cephalosporin with activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA).

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Reinheit

≥98%

Produkteigenschaften

• ALogP: -0.454
• hba_count: 8
• HBD-Zahl: 2
• Rotationsfähige Bindung: 11

Namen und Kennungen

• Pubchem Sid: 504771468
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504771468
• Kanonisches Lächeln: CCON=C(C1=NSC(=N1)NP(=O)(O)O)C(=O)NC2C3N(C2=O)C(=C(CS3)SC4=NC(=CS4)C5=CC=[N+](C=C5)C)C(=O)O.CC(=O)[O-]
• IUPAC Name: (6R,7R)-7-[[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-3-[[4-(1-methylpyridin-1-ium-4-yl)-1,3-thiazol-2-yl]sulfanyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;acetate
• InChIKey: UGHHNQFYEVOFIV-VRDMTWHKSA-N
• INCHI: 1S/C22H21N8O8PS4.C2H4O2/c1-3-38-26-13(16-25-21(43-28-16)27-39(35,36)37)17(31)24-14-18(32)30-15(20(33)34)12(9-40-19(14)30)42-22-23-11(8-41-22)10-4-6-29(2)7-5-10;1-2(3)4/h4-8,14,19H,3,9H2,1-2H3,(H4-,24,25,27,28,31,33,34,35,36,37);1H3,(H,3,4)/b26-13-;/t14-,19-;/m1./s1
• Isomere SMILES: CCO/N=C(/C1=NSC(=N1)NP(=O)(O)O)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)SC4=NC(=CS4)C5=CC=[N+](C=C5)C)C(=O)O.CC(=O)[O-]
• Molekulargewicht: 744.74
• Reaxy-Rn: 30681712
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=30681712&ln=

Chemische und physikalische Eigenschaften

• Löslichkeit: Solubility (25°C) In vitro DMSO: 73 mg/mL (98.02 mM); Water: Insoluble; Ethanol: Insoluble
• Empfindlichkeit: Moisture sensitive
• DMSO (mg/ml) Maximale Löslichkeit: 73
• DMSO (mM) Maximale Löslichkeit: 98.0207857775868
• Wasser (mg/ml) Maximale Löslichkeit: ＜1