Cevimeline hydrochloride , CAS No.153504-70-2

CAS: 153504-70-2 Cat. No.: C275672 Summenformel: C₁₀H₁₇NOS·HCl·1/2H₂O Molekulargewicht: 199.31 (anhydrous free base ba EG-Nummer: 642-988-1 PubChem CID: 71307519

Synonyms

(+/-)-cis-2-Methylspiro[1,3-oxathiolane-5,3'-quinuclidine] | 2-METHYL-1'-AZASPIRO[[1,3]OXATHIOLANE-5,3'-BICYCLO[2.2.2]OCTANE] (HCL) | Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane], 2'-methyl-,hydrochloride | AF-102B | Cevimeline Hydrochloride Sal

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Übersicht

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Specifications

Synonyme

(+/-)-cis-2-Methylspiro[1,3-oxathiolane-5,3'-quinuclidine] | 2-METHYL-1'-AZASPIRO[[1,3]OXATHIOLANE-5,3'-BICYCLO[2.2.2]OCTANE] (HCL) | Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane], 2'-methyl-,hydrochloride | AF-102B | Cevimeline Hydrochloride Sal

Biochemische und physiologische Mechanismen

Selective M 1 and M 3 receptor agonist. Induces atropine-sensitive contractions of ilea and trachea (EC 50 values are 3.5 and 3 μM, respectively). Reverses AF64A-induced cognitive impairments and promotes saliva secretion in vivo.

Storage

Store at -20°C,Desiccated

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Hinweis

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Namen und Kennungen

• Kanonisches Lächeln: CC1OC2(CN3CCC2CC3)CS1.CC1OC2(CN3CCC2CC3)CS1.O.Cl.Cl
• IUPAC Name: (5R)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane];hydrate;dihydrochloride
• InChIKey: ZSTLCHCDLIUXJE-MMPAUJBDSA-N
• INCHI: 1S/2C10H17NOS.2ClH.H2O/c2*1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11;;;/h2*8-9H,2-7H2,1H3;2*1H;1H2/t2*8?,10-;;;/m11.../s1
• Isomere SMILES: CC1O[C@]2(CN3CCC2CC3)CS1.CC1O[C@]2(CN3CCC2CC3)CS1.O.Cl.Cl
• WGK Deutschland: 3
• PubChem CID: 71307519
• Molekulargewicht: 199.31 (anhydrous free base ba

Chemische und physikalische Eigenschaften

• Löslichkeit: Chloroform (slighty), Methanol (slightly)