CHAPS hydrate - UltraBio™, Ultra pure, ≥98% , CAS No.331717-45-4

CAS: 331717-45-4 Cat. No.: C475301 Molecular Weight: 614.88 (anhydrous basis) EC Number: 695-474-4

GRADE & PURITY UltraBio™, Ultra pure, ≥98%

Synonyms

3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate hydrate | CHAPS

Storage

Room temperature

Overview

CHAPS is a non-denaturing, zwitterionic sulfobetaine detergent. It is mild and solubilizes membrane proteins and receptors. It is useful for breaking protein-protein interactions. It is a derivative of the naturally occurring bile salts. It has small micellar molecular weight (6,150) and high critical micellar concentration (6 - 10 mM) allowing it to be removed from samples by dialysis.10mM CHAPS detergent has been used in the process of ion-exchange chromatography for improved purification.0.5 w/v of CHAPS is a component of high salt buffer in protein purification alongside HEPES, NaCl and EDTA.HEPES buffer has been used as lysis buffer in immunoprecipitation, supplemented with 1% CHAPS.

Specifications

Synonyms

3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate hydrate | CHAPS

Specifications & Purity

UltraBio™, Ultra pure, ≥98%

Storage

Room temperature

Grade

Ultra pure, UltraBio™

Purity

≥98%

Names and Identifiers

• Canonical Smiles: CC(CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C.O
• IUPAC Name: 3-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]propane-1-sulfonate;hydrate
• InChIKey: SJCUTFKCLFLIFE-JWTJKVBLSA-N
• INCHI: 1S/C32H58N2O7S.H2O/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36;/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41);1H2/t21-,22+,23-,24-,25+,26+,27-,28+,30+,31+,32-;/m1./s1
• Isomeric SMILES: C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C.O
• WGK Germany: 1
• Alternate CAS: 75621-03-3
• Molecular Weight: 614.88 (anhydrous basis)

Chemical and Physical Properties

• Solubility: H2O: 0.1M, clear, colorless

References

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