COG 133 TFA - ≥98% , CAS No.C658607

CAS: C658607 Cat. No.: C658607 Summenformel: C₉₉H₁₈₂F₃N₃₇O₂₁ Molekulargewicht: 2283.78

QUALITÄT & REINHEIT ≥98%

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

COG 133 TFA is a fragment of Apolipoprotein E (APOE) peptide. COG 133 TFA competes with the ApoE holoprotein for binding the LDL receptor, with potent anti-inflammatory and neuroprotective effects. COG 133 TFA is also a nAChR antagonist with an IC 50 of 4

Appearance:Solid

IC50& Target:IC50: 445 nM (nAChR)

In Vivo:COG 133 (1mg/kg; intratracheal administration; every other day; for 4 weeks) treatment impairs the resolution of pulmonary fibrosis in mice. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model

Biological Activity:COG 133 TFA is a fragment of Apolipoprotein E (APOE) peptide. COG 133 TFA competes with the ApoE holoprotein for binding the LDL receptor, with potent anti-inflammatory and neuroprotective effects. COG 133 TFA is also a nAChR antagonist with an IC 50 of 4

Spezifikationen

Spezifikationen & Reinheit

≥98%

Storage

Desiccated,Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

ANTAGONIST

Reinheit

≥98%

Namen und Kennungen

Molekulargewicht

2283.78

Chemische und physikalische Eigenschaften

• Löslichkeit: H2O : 50 mg/mL (21.89 mM; Need ultrasonic)