10mM in Water for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Desiccated,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Übersicht
Crocetin (Transcrocetin) disodium, extracted from saffron ( Crocus sativus L.), acts as an NMDA receptor antagonist with high affinity.
In Vitro
Crocetin (Transcrocetin, trans-Crocetin) disodium, a saffron metabolite originating from the crocin apocarotenoids, has been shown to exert strong NMDA receptor affinity and is thought to be responsible for the CNS activity of saffron.To ensure unchanged viability of Caco-2 cells throughout the transport experiments, cellular mitochondrial dehydrogenase activity of Caco-2 cells is measured by MTT assay after a 24 h incubation period with the test compounds: Hydroalcoholic saffron extract saffron extract (SE, 0.5-1 mg/mL) and crocin-1 (250-1000 µM) reveal no negative significant changes in cellular viability. Crocetin disodium at 10 µM level does not change viability while higher concentrations (40-160 µM) reduces significantly cellular viability. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
IC50& Target:NMDA Receptor
Specifications
Spezifikationen & Reinheit
10mM in Water
Biochemische und physiologische Mechanismen
Crocetin (Transcrocetin) disodium, extracted from saffron ( Crocus sativus L.), acts as an NMDA receptor antagonist with high affinity.
Storage
Desiccated,Store at -80°C
Verschickt in
Dry ice packs + Cold packs
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