CU-T12-9 - Moligand™, 10 mM in DMSO , CAS No.1821387-73-8

CAS: 1821387-73-8 Cat. No.: C1494428 Summenformel: C₁₇H₁₃F₃N₄O₂ Molekulargewicht: 362.31

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

CU-T12-9 is a specific TLR1/2 agonist with EC 50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay. CU-T12-9 activates both the innate and the adaptive immune systems. CU-T12-9 selectively activates the TLR1/2 heterodimer, not TLR2/6. CU-T12-9 signals through NF-κB and invokes an elevation of the downstream effectors TNF-α, IL-10 , and iNOS.

Specifications

Spezifikationen & Reinheit

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Aktionsart

AGONIST

Namen und Kennungen

• Isomere SMILES: CNC1=C(C=C(C=C1)[N+](=O)[O-])N2C=C(N=C2)C3=CC=C(C=C3)C(F)(F)F
• Molekulargewicht: 362.31
• Reaxy-Rn: 28978542
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=28978542&ln=

Referenzen

1. Jie Liu, Mei-qi He, Gao-peng Guan, Xin-xing Wan, Ping Jin.  (2025)  ISG15 increases the apoptosis of β cells in type 1 diabetes.  CELLULAR SIGNALLING,      [PMID:39765279] [10.1016/j.cellsig.2025.111592]

Häufig gestellte Fragen

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1821387-73-8, the molecular formula is C17H13F3N4O2, and the molecular weight is 362.31 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.