Cypermethrin - analytical standard, Moligand™ , CAS No.52315-07-8

CAS: 52315-07-8 Cat. No.: C109861 Molecular Weight: 416.3 Beilstein Registry Number: 8444118 EC Number: 257-842-9
AVAILABLE TO ORDER
GRADE & PURITY Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
Synonyms
Alphamethrine
Storage
Store at 2-8°C,Protected from light,Desiccated
Shipped In
Wet ice,FedEx DG Service
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
100mg
C109861-100mg
1

$89.90

$105.90
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250mg
C109861-250mg
2

$149.90

$174.90
Save $25.00 (14.29%)
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Why this grade

analytical standard, Moligand™ Analytical standard,Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at 2-8°C,Protected from light,Desiccated Ships Wet ice,FedEx DG Service Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 29 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
Alphamethrine
Specifications & Purity
analytical standard, Moligand™
Biochemical and Physiological Mechanisms
Synthetic pyrethroid. Interacts with sodium channels inducing cellular hyperexcitability leading to neurotoxicity. Additionally inhibits calcineurin. Active in vivo . Blood-brain barrier permeable.
Storage
Store at 2-8°C, Protected from light, Desiccated
Shipped In
Wet ice, FedEx DG Service
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Analytical standard, Moligand™
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Names and Identifiers
Pubchem Sid504750619
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504750619
Canonical SmilesCC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C
IUPAC Name[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate
InChIKeyKAATUXNTWXVJKI-UHFFFAOYSA-N
INCHI1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3
Isomeric SMILES CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C
WGK Germany 3
Alternate CAS 86753-92-6
UN Number 3077
Packing Group III
Molecular Weight 416.3
Beilstein 8444118
Reaxy-Rn 5773157
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5773157&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassLipids and lipid-like molecules
ClassFatty Acyls
SubclassFatty acid esters
Intermediate Tree Nodes Not available
Direct ParentPyrethroids
Alternative Parents Diphenylethers  Diarylethers  Benzyloxycarbonyls  Phenoxy compounds  Phenol ethers  Cyclopropanecarboxylic acids and derivatives  Carboxylic acid esters  Ketene acetals  Chloroalkenes  Vinyl chlorides  Monocarboxylic acids and derivatives  Nitriles  Carbonyl compounds  Hydrocarbon derivatives  Organic oxides  Organochlorides  Organopnictogen compounds  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Pyrethroid skeleton - Diphenylether - Diaryl ether - Benzyloxycarbonyl - Phenoxy compound - Phenol ether - Monocyclic benzene moiety - Cyclopropanecarboxylic acid or derivatives - Benzenoid - Carboxylic acid ester - Ketene acetal or derivatives - Carboxylic acid derivative - Ether - Chloroalkene - Monocarboxylic acid or derivatives - Carbonitrile - Nitrile - Haloalkene - Vinyl halide - Vinyl chloride - Carbonyl group - Organic oxygen compound - Organopnictogen compound - Organohalogen compound - Organochloride - Organonitrogen compound - Organooxygen compound - Organic oxide - Hydrocarbon derivative - Organic nitrogen compound - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as pyrethroids. These are organic compounds similar to the pyrethrins. Some pyrethroids containing a chrysanthemic acid esterified with a cyclopentenone (pyrethrins), or with a phenoxybenzyl group.
External Descriptors Pyrethroid insecticides - Pyrethroid pesticides
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLK Tbio DNA polymerase kappa (8653 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RUNX1 Tbio Runt-related transcription factor 1/Core-binding factor subunit beta (7867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Spodoptera frugiperda (784 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trichoplusia ni (986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
H4 (48 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Heliothis virescens (272 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plutella xylostella (1838 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aphis gossypii (526 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bemisia tabaci (599 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Blattella germanica (87 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Helicoverpa zea (137 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Spodoptera exigua (540 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Spodoptera litura (1708 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Helicoverpa armigera (708 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nr1i2 Nuclear receptor subfamily 1 group I member 2 (14 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Culex pipiens pallens (759 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trichogramma nubilale (84 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

16 results found

Lot NumberCertificate TypeDateItem
L2508357Certificate of AnalysisDec 16, 2025 C109861
L2508358Certificate of AnalysisDec 16, 2025 C109861
A2424089Certificate of AnalysisOct 13, 2025 C109861
A2424094Certificate of AnalysisOct 13, 2025 C109861
G2517207Certificate of AnalysisJul 21, 2025 C109861
G2517206Certificate of AnalysisJul 19, 2025 C109861
B2522129Certificate of AnalysisFeb 27, 2025 C109861
B2522130Certificate of AnalysisFeb 27, 2025 C109861
F2429194Certificate of AnalysisJul 09, 2024 C109861
A2424090Certificate of AnalysisJan 30, 2024 C109861
K2113622Certificate of AnalysisAug 04, 2023 C109861
F2307180Certificate of AnalysisJun 15, 2023 C109861
F2307178Certificate of AnalysisJun 15, 2023 C109861
B2109148Certificate of AnalysisDec 12, 2022 C109861
J2210141Certificate of AnalysisOct 17, 2022 C109861
J2210328Certificate of AnalysisOct 17, 2022 C109861

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Chemical and Physical Properties
SensitivityLight sensitive.
Refractive Index1.57
Flash Point(°C)100°C
Melt Point(°C)60-80°C
Molecular Weight416.300 g/mol
XLogP36.000
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count7
Exact Mass415.074 Da
Monoisotopic Mass415.074 Da
Topological Polar Surface Area59.300 Ų
Heavy Atom Count28
Formal Charge0
Complexity643.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count3
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Xiaomeng Sun, Yue Zhao, Ling Liu, Yuxin Qiao, Chunjuan Yang, Xiaotong Wang, Qian Li, Yang Li.  (2023)  Visual whole-process monitoring of pesticide residues: An environmental perspective using surface-enhanced Raman spectroscopy with dynamic borohydride-reduced silver nanoparticles.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:38150762] [10.1016/j.jhazmat.2023.133338]
2. Zhang Mengmei, Chen Yuan, Lai Jinghui, Wang Xingjie, Hu Kaidi, Li Jianlong, Li Qin, He Li, Chen Shujuan, Liu Aiping, Ao Xiaolin, Yang Yong, Liu Shuliang.  (2023)  Cypermethrin adsorption by Lactiplantibacillus plantarum and its behavior in a simulated fecal fermentation model.  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,  107  (22): (6985-6998).  [PMID:37702791] [10.1007/s00253-023-12764-1]
3. Cong Zhang, Bin Wan, Meng-Ru Jin, Xi Wang, Yu-Jing Wei, Ling Zhong, Bin Xia.  (2023)  Inhibition of ecdysone receptor (DcEcR) and ultraspiracle (DcUSP) expression in Diaphorina citri increased susceptibility to pesticides.  PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY,      [PMID:37532332] [10.1016/j.pestbp.2023.105518]
4. Yuhang Wan, Xinyu Yuan, Jia Liu, Ding Zhang, Zhengyong Zhang, Min Sha.  (2023)  Efficient determination of pesticides in rice by QuEChERS and UV spectroscopy in combination with chemometrics.  CEREAL CHEMISTRY,  100  (5): (1106-1113).  [PMID:] [10.1002/cche.10692]
5. Yuhang Zhang, Lu Bai, Zhirui Xu, Siyuan Chen, Junping Zheng.  (2023)  A Robust, Thermally Stable, and Efficiently Reprocessable Poly(dimethylsiloxane) Elastomers Based on Activated Dynamic Silyl Ether Linkages by Neighboring Groups.  MACROMOLECULAR CHEMISTRY AND PHYSICS,  224  (15): (2300076).  [PMID:] [10.1002/macp.202300076]
6. Xuecheng Zhu, Hongfei Su, Huilin Liu, Baoguo Sun.  (2023)  A selectivity-enhanced fluorescence imprinted sensor based on yellow-emission peptide nanodots for sensitive and visual smart detection of λ-cyhalothrin.  ANALYTICA CHIMICA ACTA,      [PMID:37032054] [10.1016/j.aca.2023.341124]
7. Ming-Kang Jin, Qi Zhang, Yu-Tian Yang, Cai-Xia Zhao, Jian Li, Hongjie Li, Haifeng Qian, Dong Zhu, Yong-Guan Zhu.  (2023)  Exposure to cypermethrin pesticide disturbs the microbiome and disseminates antibiotic resistance genes in soil and the gut of Enchytraeus crypticus.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:36812731] [10.1016/j.jhazmat.2023.131026]
8. Cong Zhang, Bin Wan, Meng-Ru Jin, Jing Wang, Tian-Rong Xin, Zhi-Wen Zou, Bin Xia.  (2023)  The loss of Halloween gene function seriously affects the development and reproduction of Diaphorina citri (Hemiptera: Liviidae) and increases its susceptibility to pesticides.  PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY,      [PMID:36963933] [10.1016/j.pestbp.2023.105361]
9. Junyu Shen, Lushan Wang, Xuxu Wang, Jiafei Xie, Tingting Yao, Yue Yu, Qi Wang, Zhen Ding, Jinpeng Zhang, Meirong Zhang, Lichun Xu.  (2022)  Cypermethrin induces apoptosis of Sertoli cells through the endoplasmic reticulum pathway.  TOXICOLOGY AND INDUSTRIAL HEALTH,      [PMID:35610186] [10.1177/07482337221104905]
10. Qidong Yu, Wende Ma, Wenmin Zhang, Hui Chen, Qingqing Ding, Yuheng Guo, Jiangfan Yang, Lan Zhang.  (2021)  In situ room-temperature rapidly fabricated imine-linked covalent organic framework coated fibers for efficient solid-phase microextraction of pyrethroids.  ANALYTICA CHIMICA ACTA,      [PMID:34556223] [10.1016/j.aca.2021.338886]
11. Xiaorong Xing, Mengwen Yan, Huilin Pang, Fu’an Wu, Jun Wang, Sheng Sheng.  (2021)  Cytochrome P450s Are Essential for Insecticide Tolerance in the Endoparasitoid Wasp Meteorus pulchricornis (Hymenoptera: Braconidae).  Insects,  12  (7): (651).  [PMID:34357311] [10.3390/insects12070651]
12. Yuxia Yang, Yue Tang, Chunxiao Wang, Bangyan Liu, Yuangen Wu.  (2021)  Selection and identification of a DNA aptamer for ultrasensitive and selective detection of λ-cyhalothrin residue in food.  ANALYTICA CHIMICA ACTA,      [PMID:34535250] [10.1016/j.aca.2021.338837]
13. Wang Heng-Xue, Zhang Rui, Li Zheng, Wang Lu-Shan, Yu Yue, Wang Qi, Ding Zhen, Zhang Jin-Peng, Zhang Mei-Rong, Xu Li-Chun.  (2021)  Cypermethrin induces Sertoli cell apoptosis through mitochondrial pathway associated with calcium.  Toxicology Research,  10  (4): (742-750).  [PMID:34484665] [10.1093/toxres/tfab056]
14. Yuheng Guo, Wenmin Zhang, Hui Chen, Qingqing Ding, Qingqing Li, Lan Zhang.  (2021)  In situ fabrication of nitrogen doped graphitic carbon networks coating for high-performance extraction of pyrethroid pesticides.  TALANTA,      [PMID:34215045] [10.1016/j.talanta.2021.122542]
15. Xiao-Chun Ma, Zong-Qin Ma, Meng-Xin Zhao, Ying-Hui Wang, Yuan Peng, Xin Guo, Fang-Huan Wang, Zhe Meng, Hao-Bo Zheng.  (2020)  Facile synthesis of magnetic molybdenum disulfide@graphene nanocomposite with amphiphilic properties and its application in solid-phase extraction for a wide polarity of insecticides in wolfberry samples.  Analytical Methods,  13  (5): (672-684).  [PMID:33475104] [10.1039/D0AY01939A]
16. Zhang Dianwei, Tang Jiaqi, Liu Huilin.  (2019)  Rapid determination of lambda-cyhalothrin using a fluorescent probe based on ionic-liquid-sensitized carbon dots coated with molecularly imprinted polymers.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  411  (20): (5309-5316).  [PMID:31254053] [10.1007/s00216-019-01912-0]
17. Xiaozhou Li, Tianyue Yang, Youtao Song, Jinghai Zhu, Deli Wang, Wei Li.  (2018)  Surface-enhanced Raman spectroscopy (SERS)-based immunochromatographic assay (ICA) for the simultaneous detection of two pyrethroid pesticides.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2018.11.112]
18. Li’na Qiao, Sihua Qian, Yuhui Wang, Hengwei Lin.  (2018)  A colorimetric sensor array based on sulfuric acid assisted KMnO4 fading for the detection and identification of pesticides.  TALANTA,      [PMID:29426516] [10.1016/j.talanta.2018.01.029]
19. Xuelian Wu, Xiaodong Lv, Jixiang Wang, Lin Sun, Yongsheng Yan.  (2017)  Surface molecular imprinted polymers based on Mn-doped ZnS quantum dots by atom transfer radical polymerization for a room-temperature phosphorescence probe of bifenthrin.  Analytical Methods,  (31): (4609-4615).  [PMID:] [10.1039/C7AY01147D]
20. Yaowei Zhu, Ruijie Tang, Jun Zhao, Changlong Jiang, Lingfei Li, Bianhua Liu.  (2025)  Design and application of metal-organic framework based chemo-fluorescent sensor for selective sensing of the full spectrum of tetracyclines in complex samples.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.160281]
21. Sitian Gu, Wenli Zhu, Yufei Liu, Huixiao Duo, Qingli Yang, Xiudan Hou.  (2025)  Ionic liquid-modified magnetic covalent organic framework for the extraction of four pyrethroids in traditional Chinese herbs.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:39874742] [10.1016/j.chroma.2025.465719]
22. Lifan Zhang, Ziyue Lang, Bozhi Lu, Tinglan Yang, Xinyi Zhang, Muxue Wang, Xiaomei Zhang, Hongmei Cao, Daixin Ye.  (2024)  Smartphone-based colorimetric paper chip sensor using single-atom nanozyme for the detection of carbofuran pesticide residues in vegetables.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:39556890] [10.1016/j.saa.2024.125415]
23. Binghai Lv, Zhenyan Zhang, Bingfeng Chen, Siqi Yu, Minglong Song, Yitian Yu, Tao Lu, Liwei Sun, Haifeng Qian.  (2024)  The effects of different halogenated-pyrethroid pesticides on soil microbial community.  SCIENCE OF THE TOTAL ENVIRONMENT,      [PMID:39644647] [10.1016/j.scitotenv.2024.177882]
24. Yahui He, Yajie Liu, Xinyu Liu, Yao Zhu, Yaling Yang, Jing Wang, Baoguo Sun.  (2024)  Visual lambda-cyhalothrin detection using yellow carbon dots molecularly imprinted polyvinylidene fluoride fluorescent membrane.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2024.136041]
25. Guoqiang Zhao, Wenjing Chen, Rongrong Zhang, Rui Zhang, Bo Jiang, Ruyan Hou, Xing Huang.  (2025)  Mechanisms of cypermethrin degradation and remediation by Rhodococcus sp. H-3: Insights from comparative genomics, hydrolase CymE1 secretory expression, and bacterial community analysis.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:40915267] [10.1016/j.jhazmat.2025.139775]
26. Hua Li, Dang Fanglin, Yu Lumengfei, Zhao Hui, Wei Ting, An Fengqiu.  (2024)  Soil residues and crop accumulation of organophosphorus and pyrethroid pesticides in agricultural fields in Shaanxi, China.  JOURNAL OF SOILS AND SEDIMENTS,  24  (7): (2713-2723).  [PMID:] [10.1007/s11368-024-03846-2]
27. Li Hua, Meiting Wang, Xinlong Wei.  (2025)  Response of Brassica chinensis L to the stress of combined pollution of microplastics and cypermethrin.  ENVIRONMENTAL TECHNOLOGY,      [PMID:40556035] [10.1080/09593330.2025.2521515]
28. Shuhua Li, Shen Zhang, Dong Li, Tianhui Jiao, Jie Wei, Xiaomei Chen, Qingmin Chen, Quansheng Chen.  (2025)  Aptamer-driven upconversion fluorescence detection of dual pesticide residues in tea.  FOOD CHEMISTRY,      [PMID:41349407] [10.1016/j.foodchem.2025.147350]
29. Fan Yu, Shihao Luo, Zhengrong Zhou, Feixia Chen, Jiawei Ying, Qiufang Wu, Yize Wu, Shihua Chen, Xinxin Yao, Feiqin Xie, Wenhui Xu, Ke Xu, Renyi Peng.  (2026)  Co-exposure to polystyrene nanoparticles and cypermethrin regulates ferroptosis-mediated hepatic steatosis via the GPX4/SREBP1/SCD1 molecular axis.  ENVIRONMENT INTERNATIONAL,      [PMID:] [10.1016/j.envint.2026.110223]
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