D-Milchsäure - Moligand™, ≥90%(T) , Agonist of HCA 1 receptor, CAS No.10326-41-7, Agonist of HCA 1 receptor

CAS: 10326-41-7 Cat. No.: S161106 Summenformel: C₃H₆O₃ Molekulargewicht: 90.08 EG-Nummer: 233-713-2

QUALITÄT & REINHEIT Moligand™, ≥90%(T)

Synonyms

(D)-(-)-Lactic acid | (R)-lactate | (R)-2-Hydroxypropionate | D-2-Hydroxypropionic acid | D-(-)-Lactate | D-LACTIC ACID [WHO-DD] | AS-19478 | HY-111095 | (R)-2-Hydroxypropionic acid(R)-2-Hydroxypropionic acid | (R)-alpha-Hydroxypropionate | D-Lactic acid

Storage

Lagerung bei -20°C

Shipped In

Eistruhe + Eispads

Übersicht

Milchsäure wird als Reagenz in der organischen Synthese (bei der Herstellung von Klebstoffen) verwendet. Sie wird in der Leder-, Textil- und Gerbereiindustrie verwendet. Sie kann als Weichmacher, als Katalysator oder als Säuerungsmittel verwendet werden. Milchsäure wurde sogar als Aromastoff bei der Herstellung von Tabakerzeugnissen verwendet.

Spezifikationen

Synonyme

(D)-(-)-Lactic acid | (R)-lactate | (R)-2-Hydroxypropionate | D-2-Hydroxypropionic acid | D-(-)-Lactate | D-LACTIC ACID [WHO-DD] | AS-19478 | HY-111095 | (R)-2-Hydroxypropionic acid(R)-2-Hydroxypropionic acid | (R)-alpha-Hydroxypropionate | D-Lactic acid

Spezifikationen & Reinheit

Moligand™, ≥90%(T)

Biochemische und physiologische Mechanismen

Bei Tieren ist Milchsäure eine Stoffwechselverbindung, die von wuchernden Zellen und unter anaeroben Bedingungen, z. B. bei anstrengender körperlicher Betätigung, produziert wird. Milchsäure kann wieder zu Pyruvat oxidiert oder über die Gluconeogenese in

Storage

Lagerung bei -20°C

Verschickt in

Eistruhe + Eispads

Note

Moligand™

Aktionsart

AGONIST

Mechanismus der Wirkung

Agonist of HCA 1 receptor

Reinheit

≥90%(T)

Namen und Kennungen

Pubchem Sid

528764015

Kanonisches Lächeln

CC(C(=O)O)O

IUPAC Name

(2R)-2-hydroxypropanoic acid

InChIKey

JVTAAEKCZFNVCJ-UWTATZPHSA-N

INCHI

1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m1/s1

Isomere SMILES

C[C@H](C(=O)O)O

Molekulargewicht

90.08

Reaxy-Rn

1209341

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1209341&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Klasse Hydroxy acids and derivatives
      • Subclass Alpha hydroxy acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Klasse: Hydroxy acids and derivatives
• Subclass: Alpha hydroxy acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Alpha hydroxy acids and derivatives
• Alternative Parents: Secondary alcohols Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Alpha-hydroxy acid - Secondary alcohol - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Alcohol - Aliphatic acyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as alpha hydroxy acids and derivatives. These are organic compounds containing a carboxylic acid substituted with a hydroxyl group on the adjacent carbon.
• External Descriptors: 2-hydroxypropanoic acid

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Zugehörige Ziele (menschlich)

HCAR1 Tchem Hydroxycarboxylic acid receptor 1 (1 Activities)

Discover Target: HCAR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC16A1 Tchem Monocarboxylate transporter 1 (146 Activities)

Discover Target: SLC16A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO2B1 Tchem Solute carrier organic anion transporter family member 2B1 (580 Activities)

Discover Target: SLCO2B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC16A3 Tchem Monocarboxylate transporter 4 (196 Activities)

Discover Target: SLC16A3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC16A7 Tchem Monocarboxylate transporter 2 (11 Activities)

Discover Target: SLC16A7

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC16A10 SLC16A10 protein (28 Activities)

Discover Target: SLC16A10

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Zugehörige Ziele (nicht menschlich)

Slco2a1 Solute carrier organic anion transporter family member 2A1 (47 Activities)

Discover Target: Slco2a1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Slc16a10 Monocarboxylate transporter 10 (73 Activities)

Discover Target: Slc16a10

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Wirkungsmechanismen

Chemische und physikalische Eigenschaften

• Löslichkeit: Soluble in water (50mg/ml)
• Empfindlichkeit: heat sensitive
• Brechungsindex: 1.43
• Spezifische Drehung [α]: 13° (C=2.5,1.5mol/L NaOH)
• Flammpunkt (°C): 110 °C
• Molekulargewicht: 90.080 g/mol
• XLogP3: -0.700
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 90.0317 Da
• Monoisotopic Mass: 90.0317 Da
• Topological Polar Surface Area: 57.500 Ų
• Heavy Atom Count: 6
• Formal Charge: 0
• Complexity: 59.100
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1