D-(-)-Quinic acid - analytical standard, ≥98% , CAS No.77-95-2

CAS: 77-95-2 Cat. No.: Q109706 Molecular Weight: 192.17 Beilstein Registry Number: 2212412 EC Number: 201-072-8
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GRADE & PURITY Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. ≥98%
Synonyms
NSC1115 | Quinic acid, United States Pharmacopeia (USP) Reference Standard | 4gui | MEGxp0_001735 | SCHEMBL23845421 | 1L-1(OH),3,4/5-Tetrahydroxycyclohexanecarboxylic acid | BSPBio_003137 | Cyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, (1.alpha.,3R,4
Storage
Room temperature
Shipped In
Normal
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Size
Status
Price
Qty
500mg
Q109706-500mg
8
$56.90
1g
Q109706-1g
2
$89.90
5g
Q109706-5g
3
$314.90
10g
Q109706-10g
3
$539.90
25g
Q109706-25g
1
$1,149.90
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Why this grade

analytical standard, ≥98% Analytical standard for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 19 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

D-(-)-Quinic acid, a plant metabolite, is chiral building block used in multistep chemical synthesis of natural compounds.

Application
D-(−)-Quinic acid can be used as:      
A chiral selector electrolyte along with copper(II) sulfate. This electrolyte is utilized in chiral resolution DL-tartaric acid by ligand-exchange capillary electrophoresis method.      
A starting material in the synthesis of stereoisomers of 3,4,6-trihydroxyazepanes, 7-hydroxymethyl-3,4,5-trihydroxyazepanes, and 3,4,5-trihydroxyazepanes, as potential inhibitors of glycosidase.        
A precursor for the preparation of trihydroxy piperidine derivatives and (+)-proto-quercitol glycosidase inhibitors.

Specifications

Synonyms
NSC1115 | Quinic acid, United States Pharmacopeia (USP) Reference Standard | 4gui | MEGxp0_001735 | SCHEMBL23845421 | 1L-1(OH), 3, 4/5-Tetrahydroxycyclohexanecarboxylic acid | BSPBio_003137 | Cyclohexanecarboxylic acid, 1, 3, 4, 5-tetrahydroxy-, (1.alpha., 3R, 4
Specifications & Purity
analytical standard, ≥98%
Storage
Room temperature
Shipped In
Normal
Grade
Analytical standard
Purity
≥98%
Names and Identifiers
Canonical SmilesC1C(C(C(CC1(C(=O)O)O)O)O)O
IUPAC Name(3R,5R)-1,3,4,5-tetrahydroxycyclohexane-1-carboxylic acid
InChIKeyAAWZDTNXLSGCEK-LNVDRNJUSA-N
INCHI1S/C7H12O6/c8-3-1-7(13,6(11)12)2-4(9)5(3)10/h3-5,8-10,13H,1-2H2,(H,11,12)/t3-,4-,5?,7?/m1/s1
Isomeric SMILES C1[C@H](C([C@@H](CC1(C(=O)O)O)O)O)O
WGK Germany 3
RTECS GU8650000
Molecular Weight 192.17
Beilstein 2212412
Reaxy-Rn 2693888
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2693888&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic oxygen compounds
ClassOrganooxygen compounds
SubclassAlcohols and polyols
Intermediate Tree Nodes Cyclic alcohols and derivatives - Cyclitols and derivatives
Direct ParentQuinic acids and derivatives
Alternative Parents Cyclohexanols  Alpha hydroxy acids and derivatives  Tertiary alcohols  Polyols  Monocarboxylic acids and derivatives  Carboxylic acids  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic homomonocyclic compounds
Substituents Quinic acid - Cyclohexanol - Hydroxy acid - Alpha-hydroxy acid - Tertiary alcohol - Secondary alcohol - Polyol - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic oxide - Hydrocarbon derivative - Carbonyl group - Aliphatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as quinic acids and derivatives. These are compounds containing a quinic acid moiety (or a derivative thereof), which is a cyclitol made up of a cyclohexane ring that bears four hydroxyl groups at positions 1,3.4, and 5, as well as a carboxylic acid at position 1.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
APP Tclin Amyloid-beta A4 protein (8510 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MT2 (2907 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Sele Selectin E (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Selp P-selectin (7 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
pol Human immunodeficiency virus type 1 integrase (9041 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human immunodeficiency virus 1 (70413 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

12 results found

Lot NumberCertificate TypeDateItem
G2220853Certificate of AnalysisJan 19, 2026 Q109706
D2621070Certificate of AnalysisJun 09, 2025 Q109706
F2526626Certificate of AnalysisJun 09, 2025 Q109706
F2526627Certificate of AnalysisJun 09, 2025 Q109706
F2526633Certificate of AnalysisJun 09, 2025 Q109706
F2526634Certificate of AnalysisJun 09, 2025 Q109706
F2526635Certificate of AnalysisJun 09, 2025 Q109706
F2526640Certificate of AnalysisJun 09, 2025 Q109706
F2526642Certificate of AnalysisJun 09, 2025 Q109706
J2414405Certificate of AnalysisOct 28, 2024 Q109706
A2205335Certificate of AnalysisOct 07, 2023 Q109706
K1913035Certificate of AnalysisJun 06, 2023 Q109706

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Chemical and Physical Properties
Specific Rotation[α]-43.5 ° (C=10, H2O)
Melt Point(°C)166-168°C
Molecular Weight192.170 g/mol
XLogP3-2.400
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count6
Rotatable Bond Count1
Exact Mass192.063 Da
Monoisotopic Mass192.063 Da
Topological Polar Surface Area118.000 Ų
Heavy Atom Count13
Formal Charge0
Complexity203.000
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Citations of This Product
References
1. Tiantian Wan, Zulei Zhang, Hailong Wang, Yiwen Yang, Hanxing Yang, Jian Zhang, Yanbo Zeng, Lei Li, Jinchun Li.  (2022)  Rapid and highly selective detection of chlorogenic acid in fruit samples by Fe3O4@SiO2@PIL with boron affinity via a fluorescence enhanced strategy.  NEW JOURNAL OF CHEMISTRY,  47  (2): (828-837).  [PMID:] [10.1039/D2NJ04750K]
2. Xi Bao, Shiyao Zhang, Xueting Zhang, Yongli Jiang, Zhijia Liu, Xiaosong Hu, Junjie Yi.  (2022)  Effects of pasteurization technologies and storage conditions on the flavor changes in acidified chili pepper.  Current Research in Food Science,      [PMID:36065197] [10.1016/j.crfs.2022.08.007]
3. Qi Quan, Wei Liu, Jiajing Guo, Meiling Ye, Juhua Zhang.  (2022)  Effect of Six Lactic Acid Bacteria Strains on Physicochemical Characteristics, Antioxidant Activities and Sensory Properties of Fermented Orange Juices.  Foods,  11  (13): (1920).  [PMID:35804736] [10.3390/foods11131920]
4. Linjun Li, Jinsuo Lu, Heliang Pang, Zhiqiang Zhang, Jing Yang, Pengpeng Li, Xiaoyu Yan, Miaomiao Fan.  (2022)  New insight into scale inhibition during tea brewing: Ca2+/Mg2+ complexing and alkalinity consumption.  Journal of Environmental Sciences,      [PMID:36182193] [10.1016/j.jes.2022.02.014]
5. Zi Ye, Zhixun Shang, Shiyao Zhang, Meiqi Li, Xuetin Zhang, Hongbing Ren, Xiaosong Hu, Junjie Yi.  (2022)  Dynamic analysis of flavor properties and microbial communities in Chinese pickled chili pepper (Capsicum frutescens L.): A typical industrial-scale natural fermentation process.  FOOD RESEARCH INTERNATIONAL,      [PMID:35227474] [10.1016/j.foodres.2022.110952]
6. Shizhong Li, Chaoning Liang, Guoxia Liu, Jian-Ming Jin, Yong Tao, Shuang-Yan Tang.  (2021)  De Novo Biosynthesis of Chlorogenic Acid Using an Artificial Microbial Community.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:33629856] [10.1021/acs.jafc.0c07588]
7. Han Peng, Zeyuan Deng, Xuan Chen, Yong Sun, Bing Zhang, Hongyan Li.  (2018)  Major chemical constituents and antioxidant activities of different extracts from the peduncles of Hovenia acerba Lindl.  INTERNATIONAL JOURNAL OF FOOD PROPERTIES,      [PMID:] [10.1080/10942912.2018.1497059]
8. Han Peng, Wenting Li, Hongyan Li, Zeyuan Deng, Bing Zhang.  (2017)  Extractable and non-extractable bound phenolic compositions and their antioxidant properties in seed coat and cotyledon of black soybean (Glycinemax (L.) merr).  Journal of Functional Foods,      [PMID:] [10.1016/j.jff.2017.03.003]
9. Pinghong Chen, Yi Wang, Lulin Chen, Wei Jiang, Yan Niu, Qing Shao, Lu Gao, Quancheng Zhao, Licheng Yan, Shufang Wang.  (2015)  Comparison of the anti-inflammatory active constituents and hepatotoxic pyrrolizidine alkaloids in two Senecio plants and their preparations by LC–UV and LC–MS.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,      [PMID:26257293] [10.1016/j.jpba.2015.07.014]
10. Peng Jiao, Liu Rongyan, Xu Junyi, Yao Yingjuan, Li Beibei, Chen Dengke, Chang Zhuangpeng, Zhao Rui, Feng Yanlin, Hou Ruigang, Lee Min, Zhang Xiao.  (2025)  Acid-responsive aggregated carrot-derived nanoantioxidants alleviate oxidative stress and restore osteoblast activity.  JOURNAL OF NANOBIOTECHNOLOGY,  23  (1): (1-27).  [PMID:40075427] [10.1186/s12951-025-03235-y]
11. Peng Yijin, Yun Yurou, Zou Wenhui, Zhou Linyan.  (2025)  Characterization of colour, phenolics, and volatile compounds of 6 pomegranate varieties grown in Yunnan.  INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY,      [PMID:] [10.1093/ijfood/vvaf007]
12. Minyu Cai, Zhiye Peng, Piqian Xu, Miao Yu, Nanxin Diao, Yong Cao, Sashuang Dong, Xiang Fang.  (2025)  Comprehensive analysis of the flavor and color characteristics of light-fermented sour tea mediated by aspergillus Niger RAF106.  FOOD CHEMISTRY,      [PMID:40154056] [10.1016/j.foodchem.2025.143866]
13. Silei Zhang, Chaofan Guo, Sakamon Devahastin, Zibo Song, Xiaosong Hu, Junjie Yi.  (2025)  Quality evaluation of delavayi juice pasteurized using a novel continuous high pressure processing technology: A combined numerical simulation and experimental analysis.  LWT-FOOD SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.lwt.2025.117481]
14. Zhang Hui-Wen, Wang Jian-Ye, Liu Yan-Yan, Tian Jing-Min, Park Jinbong, Wang Huan-Yun, Xu Ying-Qi.  (2025)  Elucidating the Anti-Atherosclerotic Mechanisms of Sanzi San: An Integrated Approach Using Serum Pharmacochemistry, Network Pharmacology, and Pharmacokinetics.  World Journal of Traditional Chinese Medicine,      [PMID:] [10.4103/wjtcm.wjtcm_49_25]
15. Minyu Cai, Liyan Huang, Sashuang Dong, Nanxin Diao, Weilian Ye, Zhiye Peng, Xiang Fang.  (2023)  Enhancing the Flavor Profile of Summer Green Tea via Fermentation with Aspergillus niger RAF106.  Foods,  12  (18): (3420).  [PMID:37761129] [10.3390/foods12183420]
16. Chengyu Jin, Xiao Wang, Xianghe Meng, Qin Ye.  (2025)  Phenolics-abundant Camellia oleifera Abel oil exhibited potential functions of atopic dermatitis amelioration.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2025.107754]
17. Yueting Zeng, La Xiang, Shizhong Li, Jian-Ming Jin, Chaoning Liang, Shuang-Yan Tang.  (2026)  Growth-Coupled Screening Enables Efficient Engineering of Key Enzymes for Chlorogenic Acid Biosynthesis.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:41641551] [10.1021/acs.jafc.5c14119]
18. Zhiyuan Lin, Mei Chen, Bo Zhou, Junfeng Tan, Liang Zeng, Zhi Lin, Jinchi Tang, Weidong Dai.  (2026)  Unraveling Variations in Primary Metabolites of Longjing Green Tea During Processing and from Different Geographical Origins.  Foods,  15  (5):   [PMID:] [10.3390/foods15050865]
19. Anna Yang, Chunmei Yuan, Siyan Huang, Zibo Song, Tao Wang, Zhijia Liu, Junjie Yi, Chuanqi Chu.  (2026)  Evaluation of Physicochemical Properties, Bioactivities, Flavor Profiles and Key Metabolites during Tamarind Pulp Fermentation by Kluyveromyces marxianus.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2026.108633]
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