Daminozide - Moligand™, ≥99% , Inhibitor of lysine demethylase 2A;Inhibitor of lysine demethylase 7A;Inhibitor of PHD finger protein 8, CAS No.1596-84-5, Inhibitor of lysine demethylase 2A;Inhibitor of lysine demethylase 7A;Inhibitor of PHD finger protein 8
Daminozide - Moligand™, ≥99% , Inhibitor of lysine demethylase 2A;Inhibitor of lysine demethylase 7A;Inhibitor of PHD finger protein 8, CAS No.1596-84-5, Inhibitor of lysine demethylase 2A;Inhibitor of lysine demethylase 7A;Inhibitor of PHD finger protein 8
GRADE & PURITYMoligand™?Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.≥99%
Moligand™, ≥99% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Argon charged,Room temperature Ships Normal Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Product Introduction
Daminozide is a commonly used plant growth regulator, which acts by inhibiting 2-oxoglutarate-dependent dioxygenase activity in the gibberellin biosynthesis pathway.
Application
Daminozide may be used as a reference standard for the determination of daminozide in fruits and vegetables by liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS). It may also be used as a reference standard for the determination of daminozide in Ophiopogon japonicus plants and soil by ultra-performance liquid chromatography-triple quadrupole tandem mass spectrometry (UPLC-QqQ-MS/MS). Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Description: IC50 Value: N/A Inhibition of shoot elongation in dwarf and tall peas by the 1, 1-dimethylhydrazide of succinic acid (B-995) was correlated with the inhibition of the oxidation of tryptamine-2-C(14) to indoleacetaldehyde-2-C(14) in homogenates
Storage
Argon charged, Room temperature
Shipped In
Normal
Grade
Moligand™
Action Type
INHIBITOR
Mechanism of action
Inhibitor of lysine demethylase 2A;Inhibitor of lysine demethylase 7A;Inhibitor of PHD finger protein 8
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This compound belongs to the class of organic compounds known as straight chain fatty acids. These are fatty acids with a straight aliphatic chain.
External Descriptors
Pesticides
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
1.Pengshuai Zhang, Jixiu Deng, Xiaoyu Jiang, Liang Xu, Yu Huang, Han Sun, Mi Gao, Xianghan Wang, Yulong Gao, Kangning Fan, Lu Zhang, Shuoye Yang. (2023) Equilibrium solubility and thermodynamic study of daminozide in twelve neat solvents from (283.15 to 323.15) K. JOURNAL OF CHEMICAL THERMODYNAMICS, [PMID:][10.1016/j.jct.2023.107202]
2.Linlu Shen, Hongyi Wang, Jing Kang, Jimin Shen, Pengwei Yan, Yingxu Gong, Jiaxu Zhang, Gang Fu, Shuyu Wang, Yizhen Cheng, Shengxin Zhao, Zhonglin Chen. (2023) Simultaneous elimination of N,N-dimethylhydrazine compounds and its oxidation by-product N-nitrosodimethylamine by UV-activated peroxymonosulfate process: Multiple-path mechanism validation and toxicity alteration. CHEMICAL ENGINEERING JOURNAL, [PMID:][10.1016/j.cej.2023.145837]
3.Lan Sang, Shuyu Yang, Ying Zhu, Zhigang Zhu, Binrui Yang, Ziguang Li, Xin Mao, Siling Chen, Chengsi Li, Jun Du, Xiao Zheng, Hua He, Jianheng Zheng, Yin Huang. (2024) The combined use of B vitamins and probiotics promotes B vitamin absorption and increases Akkermansia abundance. Food & Function, [PMID:38860333][10.1039/D4FO01805B]
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