Dantrolene - Moligand™, 10 mM in DMSO , CAS No.7261-97-4

CAS: 7261-97-4 Cat. No.: D1495704 Summenformel: C₁₄H₁₀N₄O₅ Molekulargewicht: 314.25 EG-Nummer: 230-684-8 PubChem CID: 6914273

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

Dantrolene is an orally active, non-competitive glutathione reductase inhibitor with a K i of 111.6 μM and an IC 50 of 52.3 μM. Dantrolene is also a calcium channel protein inhibitor. Dantrolene inhibits the release of Ca 2+ from RyR1 and RyR3, which can be beneficial in a variety of pathologies caused by disruptions in calcium homeostasis (e.g., stroke, ischemia/reperfusion injury, and neurodegenerative diseases). Dantrolene offers relief of muscle spasms, malignant hyperthermia, and antitoxic, antipyretic, and anti-inflammatory properties.

Specifications

Spezifikationen & Reinheit

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Aktionsart

INHIBITOR

Namen und Kennungen

• Isomere SMILES: C1C(=O)NC(=O)N1/N=C/C2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-]
• Alternative CAS-Nummer: 7261-97-4,833480-90-3
• PubChem CID: 6914273
• MeSH-Eintrag: Dantrium;Dantrolene;Dantrolene Sodium;Sodium, Dantrolene
• Molekulargewicht: 314.25