DDR Inhibitor - 10mM in DMSO , CAS No.1644069-80-6

CAS: 1644069-80-6 Cat. No.: D656736 Molecular Weight: 417.44 PubChem CID: 86764579

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

DDR Inhibitor is a potent discoidin domain receptor (DDR) inhibitor, with an IC 50 of 3.3 nM for DDR2 , and shows 53% inhibition on DDR1 at 1.5 nM.

In Vitro

DDR Inhibitor (Example 6) is a potent DDR inhibitor, with an IC 50 of 3.3 nM for DDR2, and shows 53% inhibition on DDR1 at 1.5 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:IC50: 3.3 nM (DDR2), IC53: 1.5 nM (DDR1)

Specifications

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

DDR Inhibitor is a potent discoidin domain receptor (DDR) inhibitor, with an IC 50 of 3.3 nM for DDR2 , and shows 53% inhibition on DDR1 at 1.5 nM.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Isomeric SMILES: CC1=C(C=C(C=C1)CNC(=O)NC2=CC(=CC=C2)F)NC(=O)C3=CN=C4N3C=CC=C4
• PubChem CID: 86764579
• Molecular Weight: 417.44

Associated Targets(Human)

DDR2 Tchem Discoidin domain-containing receptor 2 (2 Activities)

Discover Target: DDR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DDR1 Tchem Epithelial discoidin domain-containing receptor 1 (0 Activities)

Discover Target: DDR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KIT Tclin Mast/stem cell growth factor receptor Kit (1 Activities)

Discover Target: KIT

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)