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DDX3-IN-2 - ≥99% , CAS No.1919828-81-1
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GRADE & PURITY ≥99%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
🌎 Ship to: United States
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Why this grade
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Übersicht
DDX3-IN-2 is an active DEADbox polypeptide 3 ( DDX3 ) inhibitor with an IC 50 value of 0.3 μM. DDX3-IN-2 shows a broad spectrum of antiviral activity. DDX3-IN-2 has the potential to overcome HIV resistance
In Vitro
DDX3-IN-2 behaves as a competitive inhibitor with respect to the RNA substrate, which can be seen by the decrease in its inhibition potency as a function of increasing RNA substrate concentrations. DDX3-IN-2 is found to be completely inactive against the ATPase of DDX3, DDX1 helicase, and DENV NS3 helicase. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
DDX3-IN-2 (20 mg/kg; tail vein injection) possesses excellent biocompatibility, and Wistar rats shows a good tolerance to the dose of 20 mg/kg . DDX3-IN-2 (10 mg/kg; i.v. bolus injection; 0~25 hours) rapidly eliminates the half-life elimination and the plasmatic clearance values . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Wistar rats Dosage: Tail vein injection Administration: 20 mg/kg Result: Possessed excellent biocompatibility, and Wistar rats showed a good tolerance to the dose of 20 mg/kg. Animal Model: Rats Dosage: I.v. bolus injection (Pharmacokinetic Analysis) Administration: 10 mg/kg; 0~25 hours Result: Rapidly eliminated the half-life elimination and the plasmatic clearance values.
Form:Solid
IC50& Target:HIV
Specifications
Spezifikationen & Reinheit
≥99%
Biochemische und physiologische Mechanismen
DDX3-IN-2 is an active DEADbox polypeptide 3 ( DDX3 ) inhibitor with an IC 50 value of 0.3 μM. DDX3-IN-2 shows a broad spectrum of antiviral activity. DDX3-IN-2 has the potential to overcome HIV resistance.
Storage
Store at -20°C
Verschickt in
Ice chest + Ice pads
Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.
Aktionsart
INHIBITOR
Reinheit
≥99%
Namen und Kennungen
| Molekulargewicht | 349.43 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemische und physikalische Eigenschaften
| Löslichkeit | DMSO : 100 mg/mL (286.18 mM; Need ultrasonic) |
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